摘要
Wound-healing diseases present complex challenges,and proliferative vitreoretinopathy(PVR)has been a problem in the surgical retina for 50y.PVR is a prolonged and abnormal healing response to retinal injury,such as primary retinal detachment(RD)or post-RD surgery,characterized by the formation of pre/subretinal membranes,retinal gliosis and shortening,retinal pigment epithelium cell(RPE)proliferation,and increased activity of glial cells(mainly Müller cells).
