灵性健康在宫颈癌患者负性信息注意偏向与癌症进展恐惧间的中介效应

Mediating effect of spiritual health on the relationship between attention bias to negative information and fear of cancer progression in patients with cervical cancer

目的:探讨宫颈癌患者灵性健康、负性信息注意偏向与癌症进展恐惧现状,并分析灵性健康在后两者之间的中介效应。方法:采用一般资料调查表、慢性病治疗功能评估-灵性量表-12、中文版负性信息注意量表和简化版疾病进展恐惧问卷对265例宫颈癌患者进行测评。采用Pearson分析宫颈癌患者负性信息注意偏向与癌症进展恐惧、灵性健康之间的相关性,构建结构方程模型(SEM)进行中介效应检验。结果:265例宫颈癌患者灵性健康评分(22.24±3.48)分,负性信息注意偏向评分(40.52±4.57)分,癌症进展恐惧评分(35.85±4.62)分。宫颈癌患者癌症进展恐惧与负性信息注意偏向呈正相关、与灵性健康呈负相关(P<0.05);负性信息注意偏向与灵性健康呈负相关(P<0.05)。灵性健康在负性信息注意偏向与癌症进展恐惧之间中介效应值为28.15%。结论:灵性健康在负性信息注意偏向与癌症进展恐惧之间存在中介效应,宫颈癌患者负性信息注意偏向可以通过调节灵性健康间接影响癌症进展恐惧。

Objective:To explore the current status of spiritual health,negative information attention bias and fear of cancer progression in patients with cervical cancer,and analyze the mediating effect of the former between the latter two factors.Methods:265 cervical cancer patients underwent survey using the general information questionnaire,Functional Assessment of Chronic Illness Therapy-Spiritual Well-being Scale-12,Chinese version of the Negative Information Attention Scale and simplified version of the Fear of Disease Progress.Pearson analysis was used to analyze the correlation between negative information attention bias and fear of cancer progression and spiritual health in the patients,and structural equation modeling was constructed to test for mediating effects.Results:The scoring on spiritual health,negative information attention bias and fear of cancer progression fear was(22.24±3.48),(40.52±4.57)and(35.85±4.62)points,respectively,in the 265 patients included.The fear of cancer progression was positively correlated with the attention bias to negative information,yet negatively with spiritual health(P<0.05)in the patients.The attention bias to negative information was in negative relation with spiritual health(P<0.05).The mediating effect of spiritual health between attentional bias to negative information and fear of cancer progression was 28.0%.Conclusion:The mediating effect of spiritual health between negative information attention bias and fear of cancer progression is confirmed,which suggests that cervical cancer patients′attention bias to negative information can indirectly affect fear of cancer progression by regulating spiritual health.