美国结直肠外科医生协会直肠癌临床实践指南2023增补要点解读

Interpretation of the American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Rectal Cancer 2023 Supplement

直肠癌手术极具技术挑战性,并与胃肠道、泌尿系统和性功能的重大改变以及生活质量下降有关。直肠癌的治疗发展迅速,新数据不断涌现。对比2020年版美国结直肠外科医师协会直肠癌诊疗临床实践指南,2023年增补版指南对直肠癌治疗中长久以来及新近出现的问题提供了新的循证推荐,包括上段直肠癌治疗、全程新辅助治疗、新辅助后临床完全缓解患者的等待观察策略、经肛全直肠系膜切除术的安全性。

Surgery for rectal cancer is highly technically challenging and often results in significant changes to the gastrointestinal,urinary,and sexual function,with impact on quality of life.The treatment of rectal cancer has advanced rapidly,with new data continually emerging.The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Rectal Cancer 2023 Supplement introduces new evidence-based recommendations addressing both longstanding and emerging issues,compared to the 2020 edition.These updates include treatment strategies for upper rectal cancer,the use of total neoadjuvant therapy,the adoption of a watch-and-wait strategy for patients who achieve a clinical complete response after neoadjuvant therapy,and the safety of transanal total mesorectal excision.