摘要
目的:分析达芬奇机器人手术系统在早期宫颈癌保留生育功能手术中的临床应用效果。方法:回顾性分析空军军医大学第一附属医院2013年12月—2021年12月使用达芬奇机器人手术系统完成的11例保留生育功能早期宫颈癌患者的临床资料,统计分析患者术后是否补充切除子宫、月经恢复情况、是否受孕、是否复发等。结果:11例患者至今均存活,未复发,2例切除子宫,其余9例月经均正常,其中2例已成功受孕并足月分娩,7例尚未受孕;目前已求助辅助生殖技术者3例,领养子女者1例。结论:机器人手术系统应用于早期宫颈癌保留生育功能手术安全、有效,为年轻需要保留生育功能的早期宫颈癌患者提供了新的选择,但其应用优势及妊娠结局仍需长期多中心临床试验来验证。
Objective:To analyze the clinical application effect of Da Vinci robot-assisted fertility-sparing surgery for early stage cervical cancer.Methods:11 cases of Da Vinci robot-assisted fertility-sparing surgery performed in the First Affiliated Hospital of the Air Force Military Medical University from December 2013 to December 2021 were retrospectively analyzed.Patients had hysterectomy after surgery or not and their menstrual recovery,pregnancy and recurrence rate were statistically analyzed.Results:All 11 patients survived and no recurrence was found so far.Among them,2 patients had hysterectomy,and normal menstruation was found in the rest 9 patients.2 patients were successfully conceived and delivered to term,while 7 patients had not yet conceived.At present,3 patients have turned to assisted reproductive technology,and 1 patient adopted a child.Conclusion:The robotic surgical system is safe and effective in fertility-sparing surgery for patients with early stage cervical cancer,which provides a new option for young patients with early-stage cervical cancer who need fertility preservation.However,its application advantages and pregnancy outcomes should be confirmed by long-term multicenter clinical trials.
作者
李玲霞
陈必良
刘淑娟
吕小慧
周福兴
谭明华
LI Lingxia;CHEN Biliang;LIU Shujuan;LYU Xiaohui;ZHOU Fuxing;TAN Minghua(Department of Obstetrics and Gynecology,First Affiliated Hospital of the Air Force Military Medical University,Xi’an 710032,China;Hospital of Obstetrics and Gynecology,Xi’an People’s Hospital/Xi’an Fourth Hospital,Xi’an 710004,China)
基金
国家自然科学基金面上项目(81972440)
西安市人民医院(西安市第四医院)科研孵化基金联合科研项目(LH-16)。