血常规联合C反应蛋白检验在儿科细菌性感染性疾病中的诊断价值

Diagnostic Value of Blood Routine Combined with C-reactive Protein Test in Pediatric Bacterial Infectious Diseases

目的探究血常规联合C反应蛋白(CRP)检验对儿科细菌性感染性疾病的鉴别诊断价值。方法以上高县人民医院儿科2022年9月-2023年9月收治的62例感染性疾病患儿为研究对象,其中细菌性感染患儿共31例,病毒性感染患儿共31例,另取同期体检健康儿童31例。检测三组患儿血常规[白细胞计数(WBC)]与CRP水平,比较细菌性感染患儿、病毒性感染患儿与健康儿童的WBC、CRP指标,统计WBC、CRP单独及联合检验对不同细菌感染部位的检出率,分析WBC、CRP单独及联合检验对儿科细菌性感染性疾病的诊断效能。结果WBC、CRP指标由高至低依次为细菌性感染患儿>病毒性感染患儿>健康儿童(P<0.05)。WBC与CRP单独检验对不同细菌感染部位的阳性检出率比较,差异无统计学意义(P>0.05),但联合检验对不同细菌感染部位的阳性检出率高于二者单独检验(P<0.05)。WBC与CRP联合检验对儿科细菌性感染性疾病的准确性、敏感度、特异度高于其单一检验(P<0.05)。结论血常规WBC指标与CRP联合检验在儿科细菌性感染性疾病中具有较高鉴别诊断作用,其检出率、准确性、敏感度及特异度均高于其单一检验。

Objective To explore the value of blood routine combined with C-reactive protein(CRP)test in the differential diagnosis of pediatric bacterial infectious diseases.Methods A total of 62 children with infectious diseases admitted to the Department of Pediatrics of Shanggao County People's Hospital from September 2022 to September 2023 were selected as the research objects,including 31 children with bacterial infection and 31 children with viral infection.Another 31 healthy children who underwent physical examination during the same period were selected.The blood routine[white blood cell count(WBC)]and CRP levels of the three groups were detected.The WBC and CRP indexes of children with bacterial infection,children with viral infection and healthy children were compared.The detection rates of WBC and CRP alone and combined tests for different bacterial infection sites were statistically analyzed.The diagnostic efficacy of WBC and CRP alone and combined tests for pediatric bacterial infectious diseases was analyzed.Results The WBC and CRP indexes from high to low were bacterial infection>viral infection>healthy children(P<0.05),There was no significant difference in the positive detection rate of WBC and CRP in different bacterial infection sites(P>0.05).but the positive detection rate of combined test for different bacterial infection sites was higher than that of the two separate tests(P<0.05).The accuracy,sensitivity and specificity of combined test of WBC and CRP in pediatric bacterial infectious diseases were higher than those of single test(P<0.05).Conclusion The combined test of blood routine WBC index and CRP has a high differential diagnosis effect in pediatric bacterial infectious diseases,and its detection rate,accuracy,sensitivity and specificity are higher than those of single test.