羊水栓塞早期使用肝素治疗5例

5 cases of amniotic fluid embolism treated with heparin in early stage

目的 通过观察5例羊水栓塞早期应用肝素治疗的疗效来说明羊水栓塞早期使用肝素治疗的安全性及有效性。方法 选择中国人民解放军联勤保障部队第九六〇医院妇产科2015年1月至2018年12月发生羊水栓塞的5例患者为研究对象,分析羊水栓塞发病早期应用肝素后凝血改变情况及治疗效果。结果 5例患者中除1例行子宫次全切除外,其余均抢救成功,取得较为理想的效果。结论 羊水栓塞发生后在抗过敏、解除肺动脉高压的同时早期合理使用肝素治疗能减少产妇严重并发症的发生,提高抢救成功率,改善救治结局。

Objective To observe the curative effect of early heparin treatment of 5 cases of amniotic fluid embolism to show that early heparin treatment of amniotic fluid embolism is safe and effective. Methods 5 cases of amniotic fluid embolism in Department of Obstetrics and Gynecology, 960 Hospital of Joint Logistics Support Force from January 2015 to December 2018 were selected as the study objects, and the coagulation changes and therapeutic effects of heparin after the early onset of amniotic fluid embolism were analyzed. Results In 5 cases, except for 1 case of subtotal hysterectomy, all the other cases were successfully rescued, and the results were satisfactory. Conclusion Early rational use of heparin after the occurrence of amniotic fluid embolism can reduce the occurrence of serious complications, increase the success rate of rescue and improve the outcome of treatment.