正念减压疗法与舍曲林联合治疗对青少年抑郁症患者生活事件应对方式及心理健康状态的影响

The effect of mindfulness decompression therapy combined with sertraline on the coping styles for life events and mental health status of adolescent patients suffer from depression

目的 探讨分析正念减压疗法与舍曲林联合治疗对青少年抑郁症的干预效果。方法 选择2020年10月—2023年10月本院收治的青少年抑郁症患者196例作为研究对象。使用随机单盲法分为对照组和观察组两组,每组各98例。两组患者均用舍曲林进行抗抑郁治疗。对照组采取常规护理,观察组在常规护理基础上联合正念减压疗法干预。比较分析两组患者生活事件应对方式、心理健康状态、睡眠质量、生活质量等指标。结果 干预后组内比较,观察组和对照组患者生活事件应对方式、心理健康状态、睡眠质量、生活质量评分均分别优于干预前评分,差异均有统计学意义(均P<0.005)。干预后组间比较:观察组患者消极应对评分和积极应对评分分别为(8.30±1.20)分、(25.66±4.54)分,均优于对照组的(10.45±1.50)分、(21.10±4.87)分,差异均有统计学意义(均P<0.005);观察组HAMA和HAMD评分分别为(12.06±2.32)分、(11.52±2.02)分,均显著低于对照组的(15.74±2.87)分、(15.76±2.59)分,差异均有统计学意义(均P<0.005);观察组PSQI评分为(6.88±1.38)分,显著低于对照组的(9.67±3.00)分,差异具有统计学意义(P<0.005);观察组SF-36评分为(83.98±4.16)分,显著高于对照组的(78.87±3.89)分,差异具有统计学意义(P<0.005)。结论 青少年抑郁症患者采取舍曲林治疗过程中,施以正念减压疗法干预,对患者的心理健康、应对生活事件能力、睡眠质量的提高效果好,可提升整体生活质量。

Objective To explore and analyze the intervention effect of mindfulness-based stress reduction therapy combined with sertraline on adolescent depression.Methods A total of 196 adolescent patients suffer from depression who were admitted to Anding hospital from October 2020 to October 2023 were selected as study subjects.Using a randomized single-blind method,the 196 patients were divided into a control group(n=98)and an observation group(n=98).Both groups of patients were treated with sertraline.The control group received routine care,while the observation group received mindfulness-based stress reduction therapy in addition to routine care.Comparative analysis was conducted on coping strategies for life events,psychological health status,sleep quality,and quality of life between the two groups of patients.Results After intervention,compared within groups,the scores of coping strategies for life events,psychological health status,sleep quality,and quality of life of patients in the observation group and the control group were all significantly improved compared with those before intervention,with statistically significant differences(all P<0.005).Comparison between groups after intervention:The passive coping score and active coping score of patients in the observation group were(8.30±1.20)points and(25.66±4.54)points,respectively;both superior to(10.45±1.50)points and(21.10±4.87)points in the control group,with statistically significant differences(all P<0.005).The HAMA and HAMD scores of the observation group were(12.06±2.32)points and(11.52±2.02)points,both significantly lower than(15.74±2.87)points and(15.76±2.59)points of the control group,with statistically significant differences(all P<0.005).The PSQI score of the observation group was(6.88±1.38)points,and significantly lower than(9.67±3.00)points of the control group,with statistically significant difference(P<0.005).The SF-36 score of the observation group was(83.98±4.16)points,and significantly higher than(78.87±3.89)points of the control group,with statistically significant difference(P<0.005).Conclusions In the process of treating adolescent patients suffer from depression with sertraline,the intervention of mindfulness-based stress reduction therapy can effectively improve patients'psychological health,coping ability for life events,and sleep quality,thereby enhancing overall quality of life.