氯吡格雷在急诊内科中治疗急性心绞痛的效果分析

Curative Effect Analysis of Clopidogrel in Treatment of Acute Angina in Emergency Internal Medicine

目的探讨急诊内科在急性心绞痛治疗中采用氯吡格雷药物的效果。方法选取2020年1月—2023年1月本院急诊内科接诊的106例心绞痛患者为研究对象,根据治疗方式将其分为基础组(n=53)与联合组(n=53)。基础组采取心绞痛常规治疗措施,联合组在常规治疗基础上应用氯吡格雷药物治疗,比较各组患者的临床疗效。结果治疗后,联合组患者的治疗效果较基础组更为显著(P<0.05);联合组症状改善率明显高于基础组(P<0.05);联合组患者的生活质量提升较基础组更为显著(P<0.05);基础组患者出现不良反应状况的人数多于联合组(P<0.05)。结论在对急性心绞痛的治疗中,在常规治疗基础上配合氯吡格雷药物治疗,临床疗效显著,可有效改善患者临床症状,减少心绞痛发病次数与时间,且不良反应较少,可显著提升患者生活质量,临床可广泛推广。

Objective To analyze curative effect of clopidogrel in treatment of acute angina in emergency medicine deeply,and improve symptoms and reduce pains of patients.Methods The paper chose 106 patients with angina in emergency department of our hospital from January 2020 to January 2023 as experimental subjects.After admission,patients were fully informed of experimental research content and participated in each group,including basic group(53 cases)and combination group(53 cases),treated with routine treatment,angina and clopidogrel based on routine treatment.Clinical effect of each group was compared,ideal treatment for angina was analyzed.Results There was significant difference in clinical curative effect between two groups,P<0.05,combination group had more significant curative effect.There was significant difference in clinical effect between combination group and basic group(P<0.05),that of combination group was significantly higher than basic group,with improvement rate of 98.11%and 88.68%respectively.There was significant difference in life quality(P<0.05),combination group had significant better life quality.13 cases in basic group experienced adverse reactions,while 3 cases in combination group experienced adverse reactions.There was significant difference in incidence of adverse reactions between two groups(P<0.05),with 24.53%in basic group and 5.66%in combination group.Combination group had better effect for incidence adverse reactions.Conclusion During process of acute angina treatment in emergency internal medicine,combination of routine treatment and clopidogrel medication can achieve ideal clinical effect,can improve clinical symptoms of patients,reduce frequency and duration of angina effectively,with fewer adverse reactions,and improve life quality of patients significantly,which can be widely promoted in clinical practice.