奥美拉唑肠溶胶囊与地衣芽孢杆菌活菌胶囊联合治疗急性胃肠炎的效果评价

Curative Effect Evaluation of Omeprazole Enteric Coated Capsules Combined with Bacillus Licheniformis Capsules in Treatment of Acute Gastroenteritis

目的评价分析奥美拉唑肠溶胶囊联合地衣芽孢杆菌活菌胶囊治疗急性胃肠炎的临床效果。方法选取2023年1—6月本院收治的130例急性肠胃炎患者为研究对象,按照随机抽签分组方式将其划分为对照组(n=65)和观察组(n=65)。对照组只采用奥美拉唑肠溶胶囊进行治疗,观察组采用奥美拉唑肠溶胶囊联合地衣芽孢杆菌活菌胶囊用药方式进行治疗。对比分析两组治疗效果、症状改善时间、用药不良反应等情况。结果观察组临床效果优于对照组(P<0.05);观察组症状改善时间短于对照组(P<0.05);观察组用药不良反应总发生率小于对照组(P<0.05)。结论奥美拉唑肠溶胶囊与地衣芽孢杆菌活菌胶囊联合治疗急性肠胃炎具有显著的临床效果,能较好地改善患者腹痛、恶心、腹泻等临床症状,对患者机体损伤较轻。

Objective To evaluate and analyze clinical effect of omeprazole enteric coated capsules combined with bacillus licheniformis capsules in treatment of acute gastroenteritis.Methods The paper chose 130 patients with acute gastroenteritis in our hospital from January to June 2023 as study subjects,and divided them into two groups randomly by drawing lots.Red label patients in observation group(n=65)were treated with omeprazole enteric coated capsules combined with bacillus licheniformis capsules,while blue label patients in control group(n=65)with omeprazole enteric coated capsules only.Clinical effect,symptom improvement time,adverse drug reactions,APACHEIII scores and treatment time(condition scores,gastrointestinal function scores,hospital stay,treatment cost)were compared and analyzed between two groups.Results Clinical effect,symptom improvement time,adverse drug reactions,APACHEIII scores,and treatment time(disease status scores,gastrointestinal function scores,length of stay,treatment cost)in observation group were better than control group,data comparison was significant(P<0.05).Conclusion Combination of omeprazole enteric coated capsules and bacillus licheniformis capsules can achieve significant clinical effect in treatment of acute gastroenteritis,can improve clinical symptoms effectively,including abdominal pain,nausea,and diarrhea in patients,with fewer adverse reactions,less damage to body of patients,shorter treatment time,lower cost,and ideal overall effect evaluation,which is worthy of clinical application and promotion.