胸外科基础研究的现状与展望

The status quo and outlook of fundamental research in thoracic surgery

目前肺癌的发病率和死亡率位居第一,国内食管癌患者人数占全世界一半以上,胸外科作为这两种疾病的诊治一线正面临前所未有的挑战。以手术为主,化疗、靶向治疗、免疫治疗为辅的治疗模式在不断的更新迭代,随着"空间单细胞多组学"、"更高层次的多模态"、"更深层次的学科交叉融合"等概念的出现,为胸外科的基础研究带来了机遇和挑战。我们胸外科医师应该在时代的潮流中,激流勇进,迎难而上,在基础研究领域深耕细作,促进基础向临床的转化,为胸外科的发展添砖加瓦。

China currently has the highest number of esophageal cancer patients in the world,and lung cancer has the highest incidence and fatality rates globally.Thoracic surgery,being the primary method for diagnosing and treating these conditions,faces unprecedented challenges.The surgical approach serves as the foundation of the treatment,continually evolving and improving with the integration of chemotherapy,targeted therapy,and immunotherapy.The field of thoracic surgery’s fundamental research encounters both opportunities and challenges with the emergence of concepts such as"deeper interdisciplinary integration","spatial single-cell multi-omics",and"higher-level multi-modality".The Times emphasizes that thoracic surgeons must embrace risks and confront these challenges directly.Efforts should be dedicated to advancing basic research,facilitating the translation of research findings into clinical practice,and promoting the progress of the thoracic surgery profession.