将息疗法结合柴胡加龙骨牡蛎汤治疗老年肝郁兼痰热内扰型不寐患者临床观察

Medication and Recuperation Therapy Combined with Chaihu Longgu Muli Decoction in the Treatment of Senile Insomnia Due to Stagnation of Liver Qi and Internal Disturbance of Phlegm and Heat Type

目的探究将息疗法结合柴胡加龙骨牡蛎汤用于老年肝郁兼痰热内扰型不寐患者的临床效果。方法采用随机数字表法将2022年3月—2023年3月荆门市中医医院收治的120例肝郁兼痰热内扰型不寐患者分为观察组和对照组,各60例。对照组予右佐匹克隆片治疗,观察组在对照组的基础上予柴胡加龙骨牡蛎汤联合将息疗法治疗,比较两组睡眠质量、睡眠指标,临床效果及不良反应。结果治疗后,两组匹兹堡睡眠质量指数量表(PSQI)评分均显著降低,且观察组显著低于对照组(P<0.05);两组睡眠效率(SE)、慢波睡眠(SWS)时间均显著优于治疗前,觉醒时间(AT)均短于治疗前,且观察组SE、SWS时间显著优于对照组,AT显著短于对照组(P<0.05)。观察组治疗总有效率为91.67%(55/60),显著高于对照组的80.00%(48/60)(P<0.05);且观察组不良反应总发生率为10.00%(6/60),显著低于对照组的46.67%(28/60)(P<0.05)。结论老年肝郁兼痰热内扰型不寐患者采用将息疗法联合柴胡加龙骨牡蛎汤治疗,能够有效提高睡眠质量,改善SWS时间、SE、AT指标,效果显著,且具有较高安全性。

Objective To explore the clinical efficacy of medication and recuperation therapy combined with Chaihu Longgu Muli de⁃coction in the treatment of senile insomnia due to stagnation of liver qi and internal disturbance of phlegm and heat type.Methods A total of 120 patients with insomnia of liver depression and phlegm heat internal disturbance type admitted to Jingmen Hospital of Tra⁃ditional Chinese Medicine from March 2022 to March 2023 were randomly divided into two groups,with 60 cases in each group.The treatment group was treated with medication and recuperation therapy combined with Chaihu Longgu Muli decoction,and the control group was treated with eszopiclone.The therapeutic effect between the two groups was compared.Results After treatment,the Pitts⁃burgh sleep quality index(PSQI)score of both groups was significantly decreased,and the observation group was significantly lower than the control group(P<0.05).Sleep efficiency(SE)and slow wave sleep(SWS)time in both groups were significantly better than be⁃fore treatment,wake time(AT)was shorter than before treatment,and SE and SWS time in observation group were significantly better than control group,and AT was significantly shorter than control group(P<0.05).The total effective rate of observation group was 91.67%(55/60),which was significantly higher than that of control group(80.00%,48/60)(P<0.05).The total incidence of adverse reac⁃tions in the observation group was 10.00%(6/60),which was significantly lower than that in the control group(46.67%,28/60)(P<0.05).Conclusion The medication and recuperation therapy combined with Chaihu Longgu Muli decoction in the treatment of senile insom⁃nia due to stagnation of liver qi and internal disturbance of phlegm and heat type can effectively improve sleep quality,improve SWS time,SE,and AT indicators,and has significant effects and high safety.