维生素C加硫酸庆大霉素治疗复发性口腔溃疡的临床效果及对疼痛程度的影响

Clinical efficacy of vitamin C and gentamycin sulfate in the treatment of recurrent oral ulcer and its influence on degree of pain

目的探讨复发性口腔溃疡患者施以维生素C加硫酸庆大霉素治疗的临床效果以及对疼痛程度的影响。方法选取56例复发性口腔溃疡患者,按照治疗方式的不同分为对照组、观察组,各28例。对照组治疗方式为维生素B联合西瓜霜喷雾剂,观察组治疗方式为维生素C加硫酸庆大霉素。比较两组患者的疼痛程度、溃疡面积、进食影响程度,不良反应发生率,治疗效果。结果治疗后,观察组疼痛程度评分(0.55±0.12)分、溃疡面积(1.32±0.41)mm^(2)、进食影响程度评分(0.49±0.15)分均小于对照组的(1.02±0.33)分、(2.36±0.66)mm^(2)、(0.87±0.28)分,数据存在差异(P<0.05)。观察组不良反应发生率为3.57%,低于对照组的21.43%,数据存在差异(P<0.05)。观察组总有效率为100.00%,高于对照组的85.71%,数据存在差异(P<0.05)。结论临床针对复发性口腔溃疡患者,对其施以维生素C加硫酸庆大霉素治疗,有利于减轻疼痛程度,缩小溃疡面积,影响进食程度较少,用药安全性更高且疗效提升。

Objective To explore the clinical effect of vitamin C and gentamycin sulfate in the treatment of recurrent oral ulcer and its influence on degree of pain.Methods A total of 56 patients with recurrent oral ulcer were selected and divided into a control group and an observation group according to different treatment methods,with 28 cases in each group.The control group was treated with vitamin B combined with Xiguashuang spray,and the observation group was treated with vitamin C and gentamycin sulfate.The degree of pain,ulcer area,impact on eating,incidence of adverse reactions and treatment effect were compared between the two groups.Results After treatment,the degree of pain score of the observation group was(0.55±0.12)points,the ulcer area was(1.32±0.41)mm^(2)and the score of impact on eating was(0.49±0.15)points,which were all lower than(1.02±0.33)points,(2.36±0.66)mm^(2)and(0.87±0.28)points of the control group.The data were different(P<0.05).The incidence of adverse reactions in the observation group was 3.57%,which was lower than 21.43%in the control group(P<0.05).The total effective rate of the observation group was 100.00%,which was higher than 85.71%of the control group(P<0.05).Conclusion For patients with recurrent oral ulcer,vitamin C and gentamycin sulfate can reduce the degree of pain,reduce the ulcer area,and has less impact on eating,the safety of medication is higher and the curative effect is improved.