中药封包治疗痛风性关节炎急性发作期患者的临床效果观察

Clinical observation of patients with acute exacerbation of gouty arthritis treated by Chinese medicine encapsulation

目的观察中药封包治疗痛风性关节炎急性发作期患者的临床效果。方法60例临床确诊的痛风性关节炎急性发作期患者,通过电脑随机分成治疗组与对照组,每组30例。治疗组采用中西药内服加中药封包肿痛关节治疗,对照组仅采用中西药内服治疗。比较两组患者临床疗效及治疗前后的疼痛程度、血尿酸。结果治疗后,两组患者数字疼痛评分法(NRS)评分均低于治疗前,且治疗组患者NRS评分(1.70±1.24)分低于对照组的(3.10±1.67)分,差异具有统计学意义(P<0.05)。治疗组总有效率93.3%,高于对照组的73.3%,差异具有统计学意义(P<0.05)。治疗后,两组患者血尿酸均低于治疗前,且治疗组患者血尿酸(417.47±67.98)μmol/L低于对照组的(461.45±78.87)μmol/L,差异具有统计学意义(P<0.05)。结论中药封包治疗对痛风性关节炎急性发作期患者的疼痛程度有显著的改善作用,其作用机制可能与尿酸水平下降有关。

Objective To observe the clinical effect of patients with acute exacerbation of gouty arthritis treated by Chinese medicine encapsulation.Methods 60 clinically diagnosed patients with acute exacerbation of gouty arthritis were randomly divided into a treatment group and a control group,each with 30 cases.The treatment group was treated with Chinese and Western medicine plus Chinese medicine encapsulation,and the control group was treated with Chinese and Western medicine only.The clinical efficacy,pain degree before and after treatment,and serum uric acid were compared between the two groups.Results After treatment,the score of numerical rating scale(NRS)in both groups was lower than that before treatment;the NRS score of the treatment group was(1.70±1.24)points,which was lower than(3.10±1.67)points of the control group;the difference between groups was statistically significant(P<0.05).The total effective rate of the treatment group was 93.3%,which was higher than 73.3%of the control group,and the difference between groups was statistically significant(P<0.05).After treatment,the serum uric acid of the two groups was lower than that before treatment,and the serum uric acid of(417.47±67.98)μmol/L in the treatment group was lower than(461.45±78.87)μmol/L in the control group.The difference between groups was statistically significant(P<0.05).Conclusion Chinese medicine encapsulation therapy can significantly improve the degree of pain in patients with acute attack of gouty arthritis,and its mechanism may be related to the decrease of uric acid level.