益气养阴化瘀法对糖尿病视网膜病变患者血糖水平及炎症的影响

Effect of Yiqi Yangyin Huayu Method on Blood Glucose Level and Inflam⁃mation in Patients with Diabetic Retinopathy

目的研究益气养阴化瘀法对糖尿病视网膜病变患者血糖水平及炎症的影响。方法选取肥城市中医医院于2021年12月—2023年12月收治的90例糖尿病视网膜病变患者为研究对象,按照治疗方法的不同,分为治疗组与对照组,分别为46例、44例。对照组采取羟苯磺酸钙治疗,治疗组在对照组基础上采取益气养阴化瘀法治疗,对比两组患者的中医证候积分(视物昏花、目睛干涩、腰膝酸软、倦怠乏力、五心烦热、口燥咽干、耳鸣、总分)、血糖水平(空腹血糖、餐后2h血糖、糖化血红蛋白)、炎症因子(白细胞介素-18、肿瘤坏死因子-α、高敏C反应蛋白)、疗效。结果治疗后,治疗组中医证候积分均优于对照组,差异有统计学意义(P均<0.05)。治疗后,两组患者的血糖水平均低于治疗前,且治疗组低于对照组,差异统计学意义(P均<0.05)。治疗后,两组各项炎症因子水平均低于治疗前,且治疗组低于对照组,差异有统计学意义(P均<0.05)。治疗组疗效优于对照组,差异有统计学意义(P<0.05)。结论益气养阴化瘀法可以缓解糖尿病视网膜病变患者的症状,同时降低血糖及炎症因子水平,提高患者的视力水平,疗效显著。

Objective To study the effect of Yiqi Yangyin Huayu method on blood glucose level and inflammation in patients with diabetic retinopathy.Methods A total of 90 patients with diabetic retinopathy admitted to Feicheng Hos-pital of Traditional Chinese Medicine from December 2021 to December 2023 were selected as the study objects.Ac-cording to different treatment methods,they were divided into treatment group and control group,46 cases and 44 cases respectively.The control group was treated with calcium dobesilate,and the treatment group was treated with Yiqi Yangyin Huayu method on the basis of the control group.The Traditional Chinese Medicine syndrome scores(dim vision,dry eyes,soreness and weakness of waist and knees,fatigue,five upset heat,dry mouth and throat,tinni-tus,total scores),plasma glucose levels(fasting plasma glucose,2-hour postprandial plasma glucose,glycated hemo-globin A1c),inflammatory factors(interleukin-18,tumor necrosis factor-α,high sensitivity C-reactive protein)and ef-ficacy were compared between the two groups.Results After treatment,the scores of Traditional Chinese Medicine syndromes in the treatment group were better than those in the control group,and the differences were statistically sig-nificant(all P<0.05).After treatment,the blood glucose levels of the two groups were lower than those before treatment,and the treatment group was lower than the control group,and the differences were statistically significant(all P<0.05).After treatment,the levels of inflammatory factors in the two groups were lower than those before treatment,and those in the treatment group were lower than the control group,and the differences were statistically significant(all P<0.05).The efficacy of the treatment group was better than that of the control group,and the difference was statistically signifi-cant(P<0.05).Conclusion Yiqi Yangyin Huayu method can relieve the symptoms of patients with diabetic retinopa-thy,reduce the levels of blood glucose and inflammatory factors,and improve the visual acuity of patients.