胰岛素泵持续皮下输注治疗2型糖尿病的控糖效果分析

Effect of Continuous Subcutaneous Infusion of Insulin Pump in the Treat⁃ment of Type 2 Diabetes Mellitus for Glycaemic Control

目的分析胰岛素泵持续皮下输注治疗2型糖尿病对血糖的影响。方法回顾性选取2021年1月—2023年12月包头市青山区二〇二医院收治的150例2型糖尿病患者的临床资料,按照治疗方式的不同分为观察组(75例,胰岛素泵持续皮下输注治疗)和对照组(75例,多次皮下注射胰岛素治疗)。比较两组血糖水平(空腹血糖、餐后2 h血糖)、胰岛素用量、空腹血糖达标时间、餐后2 h血糖达标时间、低血糖发生率。结果治疗后,观察组空腹血糖、餐后2 h血糖较对照组更低,差异有统计学意义(P均<0.05)。观察组胰岛素用量少于对照组,空腹血糖达标时间、餐后2 h血糖达标时间短于对照组,差异有统计学意义(P均<0.05)。观察组低血糖发生率低于对照组,差异有统计学意义(P<0.05)。结论胰岛素泵持续皮下输注治疗2型糖尿病能够有效控制血糖水平,减少胰岛素用量,缩短血糖达标时间,降低低血糖的发生率,安全性较高。

Objective To analyse the effect of continuous subcutaneous infusion of insulin pumps on blood glucose in the treatment of type 2 diabetes mellitus.Methods The clinical data of 150 patients with type 2 diabetes mellitus ad-mitted to Qingshan District 202 Hospital of Baotou from January 2021 to December 2023 were retrospectively se-lected.According to the difference of treatment methods,they were divided into observation group(75 cases,continu-ous subcutaneous insulin infusion by insulin pump)and control group(75 cases,multiple subcutaneous insulin injec-tion).The blood glucose levels(fasting blood glucose and 2-hour postprandial blood glucose),insulin dosage,fasting blood glucose compliance time,2-hour postprandial blood glucose compliance time,and the incidence of hypoglyce-mia were compared between the two groups.Results After treatment,the fasting blood glucose and 2-hour postpran-dial blood glucose in the observation group were lower than those in the control group,and the differences were statis-tically significant(both P<0.05).The dosage of insulin in the observation group was less than that in the control group,and the time of fasting blood glucose compliance time and 2-hour postprandial blood glucose compliance time were shorter than those in the control group,and the differences were statistically significant(all P<0.05).The incidence of hypoglycemia in the observation group was lower than that in the control group,and the difference was statistically sig-nificant(P<0.05).Conclusion Continuous subcutaneous infusion treatment with insulin pumps can effectively control blood glucose levels,reduce insulin dosage,shorten the time to reach the blood glucose target,and also reduce the oc-currence of hypoglycaemia,with a high degree of safety.