ICU危重症患者继发性肝损伤诊治的研究

The study on the diagnosis and treatment of secondary liver Injury in critically ill ICU patients

重症监护室(ICU)患者常因存在感染、低灌注、药物毒副作用等危险因素,导致继发性肝损伤发病率高。国内外已有相关研究报道ICU患者继发性肝损伤与不良预后密切相关。探索其发生的病理生理机制,了解其分型,掌握其诊断标准及个体化的治疗措施对于ICU患者继发性肝损伤的防治至关重要。本文结合国内外ICU患者继发性肝损伤的研究现状做一阐述,以期为急危重症医师提供临床参考。

Patients in Intensive Care Units(ICUs)frequently experience secondary liver injury due to various risk factors such as infections,low perfusion,and medications,leading to a high incidence of this condition.Studies from both domestic and international sources have reported that secondary liver injury in ICU patients is closely associated with poor prognoses.Exploring the pathophysiological mechanisms behind this condition,understanding its classification,and mastering the diagnostic criteria and individualized treatment strategies are crucial for the prevention and treatment of secondary liver injury in ICU patients.This article provides an overview of the current research status on secondary liver injury in ICU patients both domestically and internationally,aiming to provide clinical references for critical care physicians.