可降解聚合物血管支架结构优化设计与力学性能分析

Optimized Design and Mechanical Property Analysis of Biodegradable Polymer Vascular Stent Structure

采用一种将有限元与克里金代理模型相结合的优化方法,对设计的新型可降解聚合物血管支架结构进行多目标优化,成功得到在径向回缩率和轴向短缩率两个目标下的最优解。数值模拟结果显示,在轴向短缩率符合要求的同时,径向回缩率降低了58.21%,综合力学性能得到了改善。研究表明:基于克里金代理模型的多目标优化方法在改善血管支架的综合力学性能设计方面是有效的。

A multi-objective optimized method combining finite element and Kriging surrogate model was adopted to design a novel degradable polymer vascular stent structure,and the optimal solution was successfully obtained under the two objectives of radial shrinkage rate and axial shortening rate.The numerical results show that the radial retraction rate is reduced by 58.21%while the axial shortening rate meets the requirements,and the comprehensive mechanical properties are improved.The study shows that the multi-objective optimized method based on the Kriging agent model is effective in improving the design of the comprehensive mechanical properties of vascular stents.