急性心肌梗死患者PCI术后预后不良的影响因素分析

Analysis of influencing factors of poor prognosis after PCI in patients with acute myocardial infarction

目的:分析急性心肌梗死(AMI)患者经皮冠状动脉介入术(PCI)后预后不良的影响因素。方法:回顾性分析2022年2月至2023年2月该院收治的120例AMI患者的临床资料,随访1年,统计AMI患者PCI术后预后情况,采用Logistic回归分析AMI患者PCI术后预后不良的危险因素。结果:随访1年,AMI患者PCI术后发生预后不良28例,占23.33%,设为发生组,其余设为未发生组。发生组体质量指数(BMI)≥24 kg/m^(2)、Killip分级为Ⅲ~Ⅳ级、冠心病史、冠心病家族史、高密度脂蛋白(HDL-C)<1.00 mmol/L、低密度脂蛋白(LDL-C)≥4.10 mmol/L等占比均高于未发生组,差异有统计学意义(P<0.05);经Logistic回归分析结果显示,BMI≥24 kg/m^(2)、血清HDL-C<1.00 mmol/L、LDL-C≥4.10 mmol/L等均为影响AMI患者PCI术后预后不良的危险因素(OR>1,P<0.05)。结论:BMI≥24 kg/m^(2)、血清HDL-C<1.00 mmol/L、LDL-C≥4.10 mmol/L等均为影响AMI患者PCI术后预后不良的危险因素。

Objective:To analyze influencing factors of poor prognosis after percutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI).Methods:The clinical data of 120 patients with AMI admitted to this hospital from February 2022 to February 2023 were retrospectively analyzed.They were followed up for 1 year.The prognosis of the AMI patients after PCI was statistically analyzed.According to the occurrence of poor prognosis,Logistic regression was used to analyze the risk factors of poor prognosis in these patients with AMI after PCI.Results:After 1 year of follow-up,28 patients with AMI had poor prognosis after PCI,accounting for 23.33%,which were set as the occurrence group,and the rest were set as the non-occurrence group.The proportions of the patients with body mass index(BMI)≥24 kg/m^(2),Killip gradeⅢ-Ⅳ,history of coronary heart disease,family history of coronary heart disease,high-density lipoprotein(HDL-C)<1.00 mmol/L,low density lipoprotein(LDL-C)≥4.10 mmol/L in the occurrence group were higher than those in the non-occurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that BMI≥24 kg/m^(2),serum HDL-C<1.00 mmol/L,LDL-C≥4.10 mmol/L were all risk factors affecting the poor prognosis of the AMI patients after PCI(OR>1,P<0.05).Conclusions:BMI≥24 kg/m^(2),serum HDL-C<1.00 mmol/L,LDL-C≥4.10 mmol/L are the risk factors for poor prognosis in the patients with AMI after PCI.