血流储备分数、血清肌钙蛋白I水平联合检测对PCI术后发生MACE的预测价值

Predictive value of combined detection of fractional flow reserve and serum troponin I level for MACE after PCI

目的:探讨血流储备分数(FFR)、血清肌钙蛋白I(cTnI)水平联合检测对经皮冠状动脉介入(PCI)术后发生主要心血管不良事件(MACE)的预测价值。方法:回顾性分析2021年1月至2023年12月该院收治的80例行PCI术的冠心病患者的临床资料,根据术后住院期间是否发生MACE将其分为发生组(n=47)与未发生组(n=33)。比较两组FFR、血清cTnI水平,采用受试者工作特征(ROC)曲线分析FFR、血清cTnI水平单项及联合检测对PCI术后发生MACE的预测价值。结果:发生组FFR低于未发生组,血清cTnI水平高于未发生组,差异均有统计学意义(P<0.05);ROC曲线分析结果显示,FFR、血清cTnI水平单项及联合检测预测PCI术后发生MACE的曲线下面积分别为0.768、0.738、0.890,联合检测预测价值最高。结论:FFR、血清cTnI水平单项及联合检测对PCI术后发生MACE的预测价值高于二者单项检测。

Objective:To investigate predictive value of combined detection of fractional flow reserve(FFR)and serum cardiac troponin I(cTnI)level for major adverse cardiovascular events(MACE)after percutaneous coronary intervention(PCI).Methods:The clinical data of 80 patients with coronary heart disease who underwent PCI in this hospital from January 2021 to December 2023 were retrospectively analyzed.According to whether MACE occurred during postoperative hospitalization,they were divided into occurrence group(n=47)and non-occurrence group(n=33).The levels of FFR and serum cTnI were compared between the two groups.Receiver operating characteristic(ROC)curve was used to analyze the predictive value of single and combined detection of FFR and serum cTnI level for MACE after PCI.Results:The FFR of the occurrence group was lower than that of the non-occurrence group,the serum cTnI level was higher than that of the non-occurrence group,and the differences were statistically significant(P<0.05).The ROC curve analysis showed that the area under the curve of single and combined detection of FFR and serum cTnI level for predicting MACE after PCI were 0.768,0.738 and 0.890,respectively,and the combined detection had the highest predictive value.Conclusions:The predictive value of combined detection of FFR and serum cTnI level for MACE after PCI is higher than that of single detection.