连续性血液净化对重症心力衰竭合并肾衰竭患者心肾功能指标的影响

Continuous Blood Purification for Patients with Severe Heart Failure Com⁃plicated with Renal Failure Effects of Cardiac and Renal Function Indexes

目的探究重症心力衰竭合并肾衰竭患者应用连续性血液净化对心肾功能的改善效果。方法随机选取2018年1月—2023年12月中国人民解放军联勤保障部队第九〇三医院收治的150例重症心力衰竭合并肾衰竭患者为研究对象,根据不同治疗方法分为研究组、参照组,每组75例。参照组行血液净化治疗,研究组行连续性血液净化治疗,比较两组患者的生命体征、血气指标、心功能、肾功能。结果研究组的呼吸频率(20.19±3.51)次/min、心率(91.45±7.58)次/min、平均动脉压(83.41±3.22)mmHg优于参照组的(27.81±5.22)次/min、(106.94±8.69)次/min、(86.52±4.19)mmHg,差异有统计学意义(t=10.491、11.633、5.097,P均<0.05)。研究组的血气指标、心功能及肾功能水平均优于参照组,差异有统计学意义(P均<0.05)。结论对比常规血液净化,连续性血液净化治疗重症心力衰竭合并肾衰竭患者的效果更好,患者生命体征平稳,血气指标改善,心肾功能提高。

Objective To explore the effect of continuous blood purification on the improvement of cardiac and renal function in patients with severe heart failure and renal failure.Methods A total of 150 patients with severe heart failure and renal failure admitted to 903rd Hospital of Joint Logistic Support Force of the People's Liberation Army from January 2018 to December 2023 were randomly selected as the research objects.They were divided into study group and reference group by different treatment methods,with 75 cases in each group.The reference group was treated with blood purification,and the study group was treated with continuous blood purification.The vital signs,blood gas indexes,cardiac function and renal function of the two groups were compared.Results The respiratory rate(20.19±3.51)times/min,heart rate(91.45±7.58)times/min and mean arterial pressure(83.41±3.22)mmHg in the study group were better than those in the reference group(27.81±5.22)times/min,(106.94±8.69)times/min,(86.52±4.19)mmHg,and the differences were statistically significant(t=10.491,11.633,5.097,all P<0.05).The blood gas index,cardiac function and renal function of the study group were better than those of the reference group,the differences were statistically significant(all P<0.05).Conclusion Compared with conventional blood purification,continuous blood purification is more effective in the treatment of patients with severe heart failure and renal failure.The patients'vital signs are stable,the blood gas index is improved,and the heart and kidney function are improved.