右美托咪定联合舒芬太尼在上消化道超声内镜检查中的麻醉效果分析

Analysis of Anesthetic Effect of Dexmedetomidine Combined with Sufent⁃anil in Endoscopic Ultrasonography of Upper Gastrointestinal Tract

目的探究在上消化道超声内镜检查中右美托咪定、舒芬太尼联合应用的麻醉效果。方法随机选取2023年3月—2024年3月福建省龙岩市第二医院收治的80例行上消化道超声内镜检查的患者为研究对象,根据不同麻醉方法分为对照组(40例)、观察组(40例)。对照组使用舒芬太尼,观察组使用右美托咪定联合舒芬太尼。对比两组麻醉前、进镜即刻、进镜5 min和出镜后的血流动力学指标,围术期指标及不良反应。结果在进镜即刻、进镜5 min、出镜后,观察组血流动力学指标优于对照组,差异有统计学意义(P均<0.05)。观察组达离室标准时间短于对照组,且舒芬太尼追加次数、总用量均少于对照组,差异有统计学意义(P均<0.05)。观察组不良反应总发生率[2.50%(1/40)]低于对照组[15.00%(6/40)],差异有统计学意义(χ^(2)=3.914,P<0.05)。结论在上消化道超声内镜检查中,右美托咪定、舒芬太尼联用有利于保持血流动力学指标稳定,且不良反应发生率较低,具有一定的临床价值。

Objective To explore the anesthetic effect of dexmedetomidine combined with sufentanil in endoscopic ultrasonography of upper gastrointestinal tract.Methods A total of 80 patients who underwent upper gastrointestinal endoscopic ultrasonography in the Longyan Second Hospital from March 2023 to March 2024 were randomly selected as the research objects.According to different anesthetic methods,they were divided into control group(40 cases)and observation group(40 cases).The control group was treated with sufentanil,The hemodynamic indexes(before anesthesia,immediately after inserting the lens,5 min after inserting the lens and after extracting the lens),perioperative indexes and adverse reactions were compared between the two group.Results The hemodynamic indexes of the observation group were better than those of the control group at the time of inserthing the lens,5 min after inserthing the lens and after extrating lens,and the differences were statistically significant(all P<0.05).The time of reaching the standard of leaving the room in the observation group was shorter than that in the control group,and the additional times and total dosage of sufentanil were less than those in the control group,the differences were statistically significant(all P<0.05).The total incidence of adverse events in the observation group[2.50%(1/40)]was lower than that in the control group[15.00%(6/40)],and the difference was statistically significant(χ^(2)=3.914,P<0.05).Conclusion In upper gastrointestinal endoscopic ultrasonography,the combination of dexmedetomidine and sufentanil is beneficial to maintain the stability of hemodynamic indexes,and the incidence of adverse reactions is low,which has certain clinical value.