支架辅助弹簧圈栓塞治疗颅内动脉瘤临床治疗疗效与安全性分析

Comparison of clinical efficacy and safety of stent-assisted coil embolization for intracranial aneurysms

目的 探讨支架辅助弹簧圈栓塞治疗颅内动脉瘤临床治疗疗效与安全性分析,旨在为相关临床研究提供参考。方法 选取我院2020年12月~2022年10月收治的72例颅内动脉瘤患者作为研究对象,根据病情及手术方式不同分为2组。对照组采用单纯弹簧栓术;观察组采用支架辅助弹簧圈栓塞术。观察2组患者的临床治疗疗效和安全性。结果 (1)对照组完全治愈11例、基本治愈8例,总有效率63.33%;观察组完全治愈22例、基本治愈18例,总有效率95.24%。观察组治疗疗效明显高于对照组,对比2组患者治疗的总有效率存在明显差异具有统计学意义(P<0.05)。(2)对照组治疗期间发生不良事件8例、总发生率26.67%;观察组治疗期间发生不良事件2例、总发生率4.76%。观察组发生不良事件数显著低于对照组,对比2组患者的不良事件总发生率存在差异具有统计学意义(P<0.05)。结论 对于颅内动脉瘤患者采用支架辅助弹簧圈栓塞治疗具有确切的疗效且安全性较高,值得临床进一步推广及应用。

Objective Exploring the clinical efficacy and safety analysis of stent assisted coil embolization in the treatment of intracranial aneurysms,aiming to provide reference for related clinical research.Methods Seventy-two patients with intracranial aneurysms admitted to our hospital from December 2020 to October 2022 were selected as the study subjects.They were divided into two groups according to the condition and surgical treatment plan.The control group was treated with simple spring embolism;The study group used stent-assisted coil embolization.The clinical efficacy and safety of the two groups were observed.Results ①In the control group,ll cases were completely cured and 8 cases were basically cured,with a total effective rate of 63.33%;In the observation group,22 cases were completely cured and 18 cases were basically cured.The total effective rate was 95.24%.The therapeutic effect of the observation group was significantly higher than that of the control group,and there was a significant difference in the total effective rate between the two groups(P<0.05).②In the control group,8 cases of adverse events occurred during the treatment,with a total incidence of 26.67%;There were 2 cases of adverse events during the treatment in the observation group,with a total incidence of 4.76%.The number of adverse events in the observation group was significantly lower than that in the control group,and there was a statistically significant difference in the total incidence of adverse events between the two groups(P<0.05).Conclusion Stent-assisted coil embolization is effective and safe for patients with intracranial aneurysms,which is worthy of further clinical promotion and application.