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BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition

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摘要 Dear Editor,Ferroptosis,an iron-dependent form of cell death driven by overwhelming lipid peroxidation,represents a vulnerability in cancers,and therapeutic strategies to further potentiate ferroptosis hold great potential for melanoma treatment.
出处 《Military Medical Research》 SCIE CAS CSCD 2024年第4期620-624,共5页 军事医学研究(英文版)
基金 This work was supported by grants from the National Natural Science Foundation of China(82103183,82102803,82272849) the Natural Science Foundation of Hunan Province(2022JJ40767,2021JJ40976) the Natural Science Fund for Outstanding Youths in Hunan Province(2023JJ20093) the National Key Research and Development Program(2022YFC2504700).
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