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老年人久坐行为对认知衰弱影响的Meta分析

The effect of sedentary behavior on cognitive frailty in older adults:a meta-analysis
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摘要 目的通过Meta分析探究老年人久坐行为对认知衰弱的影响,为认知衰弱预防干预策略的制定提供参考。方法计算机检索Pubmed、Web of science、Embase、CNKI、万方和维普数据库,检索时限为建库至2022年10月,通过筛选文献、提取资料和评价纳入研究质量后,采用RevMan 5.3软件进行统计分析。结果纳入4项研究,样本量4225例,其中2项研究为横断面研究,2项为队列研究。Meta分析结果显示,老年人久坐行为与认知衰弱发生有关(OR=3.38,95%CI:1.36~8.41)。亚组分析结果显示,在不同国别[中国(OR=2.26,95%CI:1.62~3.17)、秘鲁(OR=509.43,95%CI:31.65~8200.42)]、研究场所[医院(OR=509.43,95%CI:31.65~8200.42)、社区(OR=2.22,95%CI:1.61~3.07)]、久坐的测量方法[老年人体力活动量表(OR=509.43,95%CI:31.65~8200.42)、久坐行为时间(OR=2.26,95%CI:1.62~3.17)]、随访时间[随访时间<1年(OR=2.22,95%CI:1.61~3.07)、随访时间≥1年(OR=509.43,95%CI:31.65~8200.42)]、研究类型[横断面研究(OR=2.26,95%CI:1.62~3.17)]亚组中,老年人久坐行为均与认知衰弱发生呈正相关(P<0.05)。结论老年人久坐行为与认知衰弱的发生有关,建议后续研究关注久坐行为与认知衰弱发生的内在机制,为认知衰弱的预防提供进一步的证据支持。 Objective To explore the effect of sedentary behavior on cognitive frailty in the elderly with meta-analysis,and to provide reference for the formulation of intervention strategies for the prevention of cognitive frailty.Methods Pubmed,Web of science,Embase,CNKI,Wanfang and VIP databases were searched from the establishment of the database to October 2022,and RevMan 5.3 software was used for statistical analysis after screening literature,extracting data and evaluating the quality of the included studies.Results Five studies with a sample size of 4225 were included,of which 2 were cross-sectional studies and 2 were cohort studies.The results of meta-analysis showed that sedentary behavior was associated with cognitive frailty in the elderly(OR=3.38,95%CI:1.36-8.41).The results of subgroup analysis showed that in different countries[China(OR=2.26,95%CI:1.62-3.17),Peru(OR=509.43,95%CI:31.65-8200.42)],hospital(OR=509.43,95%CI:31.65-8200.42),community(OR=2.22,95%CI:1.61-3.07),and sedentary measures[Physical Activity Scale for the Elderly(OR=509.43,95%CI:31.65-8200.42),sedentary behavior time(OR=2.26,95%CI:1.62-3.17)],follow-up time[Follow-up Time<1 Year(OR=2.22,95%CI:1.61-3.07),follow-up time≥1 Year(OR=509.43,95%CI:31.65-8200.42)],study type[Cross-sectional Study(OR=2.26,95%CI:1.62-3.17)],all of which showed that sedentary behavior was positively correlated with cognitive frailty in the elderly(P<0.05).Conclusion Sedentary behavior is related to the occurrence of cognitive frailty in the elderly,and it is suggested that follow-up studies should pay attention to the internal mechanism of sedentary behavior and cognitive frailty,so as to provide further evidence support for the prevention of cognitive frailty.
作者 刘源源 张艺雄 LIU Yuan-yuan;ZHANG Yi-xiong(Nanjing University of Chinese Medicine,Nanjing 210023,China)
机构地区 南京中医药大学
出处 《中国健康教育》 北大核心 2024年第8期681-685,690,共6页 Chinese Journal of Health Education
关键词 久坐行为 认知衰弱 老年人 Sedentary behavior Cognitive frailty Older adults
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