摘要
Purpose The patients who have nasopharyngeal carcinoma(NPC)have high possibility to metastases.Therefore,it is of great practical significance to explore the molecular mechanism of invasion and metastases in NPC.Methods Herein summarizes some molecular mechanisms reported by our previous investigation.Results Recent studies have reported the crucial roles of noncoding RNAs(ncRNAs)in tumor progression.In this letter,we summarize some newfound non-coding RNAs(miRNAs,lncRNAs,circRNAs)and coding RNAs,which could regulate invasion or metastasis in NPC by downstream genes.Conclusion We elaborated on the clinical and therapeutic implications of partial putative markers for the treatment of invasion and metastasis in NPC.
基金
supported by the grant from National Natural Science Foundation of China[No.81872192].