妇科腔镜手术患者应用七氟烷联合丙泊酚的麻醉效果研究

Study on the Anesthesia Effect of Sevoflurane Combined with Propofol in Patients Undergoing Gynecological Laparoscopic Surgery

目的分析七氟烷联合丙泊酚的麻醉方案用于妇科腔镜手术患者的麻醉效果。方法随机选取2021年12月—2022年12月大理州人民医院进行腔镜手术的70例患者作为研究对象,根据麻醉方法不同分为两组。对照组35例采用七氟烷麻醉,观察组35例采用七氟烷联合丙泊酚麻醉。比较两组患者麻醉效果,包括意识消失时间、苏醒时间、拔管时间),不同时间点生命体征,包括平均动脉压(mean arterial pressure,MAP)、心率(heart rate,HR)水平和不良反应发生情况。结果观察组患者意识消失时间、苏醒时间、拔管时间均短于对照组,差异有统计学意义(P均<0.05)。观察组插管时、手术0.5 h、拔管时和拔管后10 min的HR均低于对照组,差异有统计学意义(P均<0.05);插管时,观察组MAP高于对照组,拔管时和拔管后10 min观察组MAP低于对照组,差异有统计学意义(P均<0.05)。观察组不良反应总发生率为5.71%(2/35),低于对照组的22.85%(8/35),差异有统计学意义(χ^(2)=4.200,P=0.040)。结论妇科腔镜手术患者应用七氟烷联合丙泊酚的麻醉效果好、安全性高。

Objective To analyze the anesthetic effect of sevoflurane combined with propofol in patients undergoing gynecological endoscopic surgery.Methods A total of 70 patients who underwent endoscopic surgery in Dali People's Hospital from December 2021 to December 2022 were randomly selected as the study objects,and were divided into two groups by different anesthesia methods.Sevoflurane anesthesia was applied to 35 cases in the control group,and sevoflurane combined with propofol anesthesia was applied to 35 cases in the observation group.The anesthesia effect(time of loss of consciousness,time of recovery,time of extubation),the level of vital signs,including mean arterial pressure(MAP),heart Rate(HR)and the occurrence of adverse reactions were compared between the two groups.Results The absence time of consciousness,recovery time and extubation time in observation group were shorter than those in control group,and the differences were statistically significant(all P<0.05).The HR of the observation group at intubation,0.5 hours after operation,extubation and 10 min after extubation was lower than those of the control group,and the difference were statistically significant(all P<0.05).At intubation,the MAP of the observation group was higher than that of the control group,at extubation and 10 min after extubation,the MAP of the observation group was lower than that of the control group,and the difference were statistically significant(all P<0.05).The total incidence of adverse reactions in the observation group was 5.71%(2/35),which was lower than 22.85%(8/35)in the control group,the difference was statistically significant(χ^(2)=4.200,P=0.040).Conclusion Sevoflurane combined with propofol is effective and safe in gynecological endoscopic surgery.