头颈癌放疗患者肠内营养管理证据总结

Summary of evidence on enteral nutrition management for head and neck cancer patients receiving radiotherapy

目的系统总结头颈癌放疗患者肠内营养管理的相关证据,对证据进行总结。方法基于“6S”证据资源金字塔模型,通过计算机系统检索国内外指南网站、专业学会网站及中英文数据库中关于头颈癌放疗患者肠内营养管理相关的证据,文献类型包括指南、专家共识、证据总结,检索时限为2018年1月1日至2023年9月14日。由研究者独立进行文献筛选、数据提取和质量评价。结果共纳入19篇文献,包括10篇指南、7篇专家共识和2篇证据总结,归纳得到组织管理、营养筛查与评定、肠内营养干预方案、监测随访4个方面的内容,共67条证据。结论头颈癌放疗患者肠内营养管理证据的总结可为其规范化营养管理提供循证医学依据,推动循证医学知识向实践转化。

Objective To systematically appraise and summarize existing evidence on enteral nutrition in patients receiving radiotherapy for head and neck cancer.Methods Based on the 6S Pyramid of Evidence-based Resources,a systematic search was conducted to identify guidelines,expert consensuses,and evidence summaries related to enteral nutrition for radiotherapy patients with head and neck cancer published from January 2018 to September 2023.The search covered relevant websites of guidelines,websites of academic societies,and databases(in Chinese and English).Literature screening,quality assessment,and data extraction were performed independently by the researchers.Results A total of 19 studies were included,consisting of 10 guidelines,7 expert consensuses,and 2 evidence summaries.Four aspects and 67 items of best evidence on organizational management,nutritional screening and assessment,enteral nutritional intervention programs,and monitoring and follow-up were summarized.Conclusion This study summarized the best evidence for enteral nutrition in patients receiving radiotherapy for head and neck cancer,which can inform the standardized nutritional management and promote the translation of evidence-based knowledge into practice.