泌尿外科住院老年男性肾结石合并尿路感染患者病原微生物检验结果及耐药性分析

Pathogenic Microbial Test Results of Elderly Male Patients with Renal Stones And Urinary Tract Infection in Urology Department Hospitalization Analysis of Drug Resistance

目的探讨分析泌尿外科住院老年男性肾结石合并尿路感染患者病原微生物检验结果及耐药性。方法将新沂市人民医院2023年1月至2023年12月期间收治的住院老年男性肾结石合并尿路感染患者172例纳入研究,搜集所有患者的尿液样本,并进行病原微生物检验及耐药性分析。结果172例患者共检出病原菌172株,主要病原菌分类为革兰阴性菌、革兰阳性菌及真菌,占比分别为63.37%、22.09%、14.53%。大肠埃希菌对头孢呋辛酯、环丙沙星、左氧氟沙星的耐药性最强;肺炎克雷伯菌对头孢呋辛酯、头孢他啶的耐药性最强;肠球菌属对红霉素耐药性最强;凝固酶阴性葡萄球菌对红霉素的耐药性最强。结论住院老年男性肾结石合并尿路感染患者尿液样本中的病原菌分布广泛,其中以革兰阴性菌占比最高,且耐药性最强。

Objective:To investigate and analyze the results and drug resistance of pathogenic microorganisms in elderly male inpatients with urinary tract infection in kidney calculi.Methods:172 hospitalized elderly male patients with kidney calculi complicated with urinary tract infection in xinyi city People's Hospital from January 2023 to December 2023 were included in the study.Urine samples of all patients were collected,and pathogenic microorganisms were tested and drug resistance was analyzed.Results:A total of 172 strains of pathogenic bacteria were detected in 172 patients,and the main pathogens were classified into gram-negative bacteria、gram-positive bacteria and fungi,accounting for 63.37%、22.09%and 14.53%respectively.Escherichia coli is the most resistant to cefuroxime axetil,ciprofloxacin and levofloxacin.Klebsiella pneumoniae was the most resistant to cefuroxime axetil and ceftazidime.Enterococcus is the most resistant to erythromycin.Coagulase-negative staphylococci are the most resistant to erythromycin.Conclusion:Pathogens in urine samples of hospitalized elderly male patients with urinary tract infection in kidney calculi are widely distributed,among which Gram-negative bacteria account for the highest proportion and have the strongest drug resistance.