摘要
小檗碱是一种具有广泛药理作用的生物活性物质,除了抗炎、抗菌、抗病毒、抗高血压、抗缺氧、降血糖、降血脂等作用外,还具有抗肿瘤作用。近年来,国内外科研团体对小檗碱在抗胰腺癌领域的作用进行了诸多深入研究,取得不少重要成果。因此,该文主要就小檗碱的抗胰腺癌作用及其药理机制进行了综述,并对相关研究做了分析。
Berberine is a bioactive substance with a wide range of pharmacological effects.It has the effects against tumors in addition to anti-inflammatory,antibacterial,antiviral,antihypertensive,anti-hypoxic,hypoglycemic,and hypolipidemic effects.In recent years,domestic and foreign scientific research groups have conducted many in-depth studies on the roles of berberine in the field of anti-pancreatic cancer and achieved many important results.Therefore,the anti-pancreatic cancer effect and pharmacological mechanism of berberine are reviewed,and related studies are analyzed in this article.
作者
张明发
沈雅琴
ZHANG Ming-fa;SHEN Ya-qin(Shanghai Meiyou Pharmaceutical Co.,Ltd.,Shanghai 201204,China)
出处
《抗感染药学》
2024年第7期667-671,690,共6页
Anti-infection Pharmacy
关键词
小檗碱
抗胰腺癌作用
药理机制
berberine
anti-pancreatic cancer effect
pharmacological mechanism