基于应力场与电磁场协同治疗技术的下肢肌肉骨骼系统仿真研究

Simulation study of musculoskeletal system of lower limbs based on synergistic effects of stress and electromagnetic fields

目的:采用基于COMSOL的有限元分析方法探究应力场、电磁场协同作用下人体下肢肌肉骨骼系统产生的电场效应。方法:首先,通过Maxon Cinema 4D R21软件构建三维人体模型,并将模型以STL格式导入COMSOL 6.1软件中。其次,设计搭建针对人体左下肢的电磁场干预及应力加载模型,其中,采用的电磁场激励为15 Hz准脉冲群电流信号,应力场则是通过对人体左脚施加平均压强约为90 N/cm2的振动载荷实现。最后,通过数值模拟对人体组织内的电磁特性进行仿真计算,并在此基础上进一步比较应力场、电磁场单独以及协同干预对人体生物电场的影响。结果:仿真结果显示,在电磁场和应力场单独或协同作用下,电场强度峰值均位于腿部关节处,人体产生的生物电场强度与外源性激励加载位置的距离有关,协同作用下产生的电场相当于电磁场和应力场单独作用所引起的组织内生物电场的线性叠加。结论:该研究为预测肌肉骨骼组织内部的生物电场变化提供了数据补充,并为多物理场协同干预新疗法在下肢肌肉骨骼系统疾病治疗中的开发和应用理论奠定了基础。

Objective To apply a COMSOL-based finite element analysis method to investigating the electric field effects produced by the human lower limb musculoskeletal system under the synergistic effects of stress field and electromagnetic field.Methods Firstly,a 3D human body model was constructed by Maxon Cinema 4D R21 software,and then imported into COMSOL 6.1 software in STL format.Secondly,an electromagnetic field intervention and stress loading model for the left lower limb of the human body was designed and constructed,in which 15 Hz quasi-pulse group current signals were used for electromagnetic field excitation and the stress field was realized by applying a vibration load with an average compressive force of about 90 N/cm2 to the left foot of the human body.Finally,the electromagnetic properties of human tissue were simulated by numerical simulation,and then the effects of stress field or elecromagnetic field or combined stress field and electromagnetic field on human bioelectric field were compared.Results Simulation results showed that the electric field intensity peaked at the leg joints under both electromagnetic and stress fields acting alone or synergistically,the bioelectric field intensity generated by the human body was related to the distance from the exogenous excitation loading location,and the electric field generated under synergistic action was equivalent to the linear superposition of the bioelectric field in the tissue induced by the electromagnetic field and the stress field acting alone.Conclusion Data supplement is provided for predicting bioelectric field changes within the musculoskeletal tissue,and theoretical foundation is laid for the development and application of multi-physics field synergistic intervention therapy for treating the disorders of the lower limb musculos-keletal system.