听力损失婴幼儿短纯音听性脑干反应与IT-MAIS评分的相关性

The Correlation between Tone Burst Auditory Brainstem Response and IT-MAIS Score in Infants with Hearing Loss

目的探究听力损失婴幼儿短纯音听性脑干反应(tb-ABR)与婴幼儿有意义听觉整合量表(infant-toddler meaningful auditory integration scale,IT-MAIS)评分的相关关系。方法选择2020年11月~2023年11月我院收治的120例听力损失婴幼儿作为研究组,同时选择在医院行听力检查的健听婴幼儿50例作为对照组,患者均行tb-ABR测定及IT-MAIS评估,比较两组tb-ABR阈值与IT-MAIS评分的差异,分析tb-ABR阈值与IT-MAIS评分相关性,分析以上两项指标对听力损失的评估价值,比较不同听力损失患儿tb-ABR阈值、IT-MAIS评分,分析以上两项指标与听力损失程度的相关性。结果研究组婴幼儿平均听阈在0.5、1、2、4 kHz情况下测定tb-ABR阈值均高于对照组,IT-MAIS评分低于对照组(P<0.05);Pearson相关性分析显示,在0.5、1、2、4 kHz情况下,tb-ABR阈值与IT-MAIS评分呈负相关关系(r=-0.511,-0.432,-0.309,-0.472;P<0.05);受试者工作特征曲线显示,在0.5、1、2、4 kHz情况下测定tb-ABR阈值与IT-MAIS评分在婴幼儿听力损失诊断曲线下面积(area under the curve,AUC)值依次为0.769、0.797、0.662、0.713、0.829;随着患者听力损失程度加重,平均听阈,0.5、1、2、4 kHz情况下测定tb-ABR阈值逐渐上升,而IT-MAIS评分逐渐降低(P<0.05);Spearman相关性分析显示,tb-ABR阈值与婴幼儿听力损失程度正相关(r=0.576,0.411,0.457,0.486;P<0.05),IT-MAIS评分与婴幼儿听力损失程度负相关关系(r=-0.418;P<0.05)。结论tb-ABR与IT-MAIS存在相关性,两者不仅可以用于听力损失婴幼儿诊断,还可用于评估患儿听力损失程度。

Objective To explore the relationship between tone burst auditory brainstem response(tb-ABR)and IT-MAIS score in infants with hearing loss.Methods 120 infants with hearing loss admitted to the hospital from November 2020 to November 2023 were selected as the study group,and 50 infants with normal hearing underwent hearing examination in the hospital were selected as the control group.All the patients underwent tb-ABR measurement and IT-MAIS score evaluation.The tb-ABR threshold and IT-MAIS score of the two groups were compared and their correlation was analyzed.The value of tb-ABR threshold and IT-MAIS score for hearing loss were evaluated,while tb-ABR threshold and IT-MAIS score in infants with different hearing loss were compared,and the correlation between tb-ABR threshold,IT-MAIS score and the degree of hearing loss was analyzed.Results The tb-ABR threshold in the study group was higher than that in the control group at the average hearing thresholds of 0.5 kHz,1 kHz,2 kHz and 4 kHz,and the IT-MAIS score was lower(P<0.05).Pearson correlation analysis showed that the tb-ABR threshold was negatively correlated with the IT-MAIS score at 0.5 kHz,1 kHz,2 kHz and 4 kHz(r=-0.511,-0.432,-0.309,-0.472;P<0.05).The receiver operating characteristic curve showed that the AUC values of tb-ABR threshold and IT-MAIS score in the diagnosis of infant hearing loss were 0.769,0.797,0.662,0.713 and 0.829 respectively at the conditions of average hearing threshold,0.5 kHz,1 kHz,2 kHz and 4 kHz.With the severity of hearing loss,the tb-ABR threshold increased gradually,while the IT-MAIS score decreased at 0.5 kHz,1 kHz,2 kHz and 4 kHz(P<0.05).Spearman correlation analysis showed that the tb-ABR threshold was positively correlated with the degree of hearing loss in infants at 0.5 kHz,1 kHz,2 kHz and 4 kHz(r=0.576,0.411,0.457,0.486;P<0.05),and the IT-MAIS score was negatively correlated with the degree of hearing loss(r=-0.418;P<0.05).Conclusions tb-ABR is related to IT-MAIS,which can be used not only to diagnose hearing loss in infants,but also to assess the severity of hearing loss.