系统化管理在妇科肿瘤化疗所致恶心呕吐患者中的应用效果

Application Effect of Systematic Management in Chemotherapy-Induced Nausea and Vomiting in Patients with Gynecological Tumors

目的探讨系统化管理方案在妇科肿瘤化疗所致恶心呕吐(CINV)患者中的应用效果及患者满意度。方法选取2022年1月至2023年6月收治的妇科肿瘤行化疗患者248例,按照随机抽签法分为对照组和观察组各124例。对照组实施常规管理,观察组实施系统化管理。比较2组CINV发生率、恶心、呕吐频率及程度、心理状态[状态-特质焦虑量表]、生活质量[呕吐功能性生活指数(FLIE)]、患者满意度。结果观察组CINV发生率[46.77%(58/124)]低于对照组[67.74%(84/124)](P<0.05)。观察组恶心、呕吐频率及程度均低于对照组,FLIE量表恶心、呕吐维度及总分高于对照组(P<0.01)。观察组状态焦虑量表、特质焦虑量表评分及总分均低于干预前,且观察组低于对照组(P<0.01)。观察组满意度评价量表各项评分及总分均高于对照组(P<0.01)。结论系统化管理能有效预防妇科肿瘤化疗患者CINV,减轻恶心呕吐发生频率与程度,改善患者心理状态,提高患者生活质量及满意度。

Objective To explore the application effect and patient satisfaction of systematic management plan in chemotherapy-induced nausea and vomiting(CINV)in patients with gynecological tumors.Methods A total of 248 patients with gynecological tumors undergoing chemotherapy from January 2022 to June 2023 were selected and divided into a control group(n=124)and an observation group(n=124)according to random number table method.The control group was given routine management,while the observation group was given systematic management.The incidence of CINV,frequency and degree of nausea and vomiting,psychological state[State-Trait Anxiety Inventory(STAI)],quality of life[Functional Life Index of Emesis(FLIE)],and patient satisfaction were compared between the two groups.Results The incidence of CINV in the observation group[46.77%(58/124)]was lower than that in the control group[67.74%(84/124)](P<0.05).The frequency and degree of nausea and vomiting in the observation group were lower than those in the control group,and the nausea and vomiting dimensions and total scores on the FLIE scale were higher than those in the control group(P<0.01).The scores and total scores of STAI in the observation group were lower than those before intervention,and lower in the observation group than in the control group(P<0.01).The scores and total scores of the satisfaction evaluation scale in the observation group were higher than those in the control group(P<0.01).Conclusion Systematic management can effectively prevent CINV in patients with gynecological tumors undergoing chemotherapy,reduce the frequency and severity of nausea and vomiting,improve patients'psychological state,and enhance their quality of life and satisfaction.