多模态功能磁共振成像技术观察脑小血管病与血管性认知障碍关系的研究进展

Developments on the relationship between cerebral small vascular disease and vascular cognitive impairment by multimodal functional magnetic resonance imaging

脑小血管病(cerebral small vessel disease,CSVD)是一类广泛的脑血管疾病,病因多种多样,是导致血管性痴呆的最常见病因。随着年龄增加,CSVD的患病率也增加,影响着老年人群的生活质量。随着对传统磁共振成像技术的不断探索及应用,功能磁共振技术得到了快速发展,有希望为CSVD的早期诊断及发现其与血管性认知障碍的关系提供更多的可能性。现从多模态功能磁共振成像技术在观察CSVD与血管性认知障碍关系中的应用及研究进展进行综述,以期从影像的视角为CSVD的临床诊断提供依据。

Cerebral small vessel disease(CSVD)is a wide range of cerebrovascular diseases with a variety of causes,which is the most common cause of vascular dementia.With increasing age,the prevalence of CSVD also increases,affecting the quality of life of the elderly population.With the continuous exploration and application of traditional magnetic resonance imaging technology,functional magnetic resonance technology has been rapidly developed,and it is expected to provide more possibilities for the early diagnosis of CSVD and the relationship between CSVD and vascular cognitive impairment.This article reviews the application and research advances of multimodal functional magnetic resonance imaging in observing the relationship between CSVD and vascular cognitive impairment in order to provide evidence for the clinical diagnosis of CSVD from the perspective of imaging.