妊娠晚期急性胰腺炎发生的影响因素分析

Influencing factors for the occurrence of acute pancreatitis during late trimester of pregnancy

目的分析妊娠晚期急性胰腺炎发生的影响因素。方法314例孕28~30周妇女中,发生急性胰腺炎51例(病例组),未发生急性胰腺炎263例(对照组)。分析两组临床资料,采用多因素logistic回归分析妊娠晚期急性胰腺炎发生的影响因素。结果病例组高脂血症比例、胆道系统疾病比例和TG、ALT水平均高于对照组(P<0.05)。有高脂血症、有胆道系统疾病、高水平TG、高水平ALT是妊娠晚期急性胰腺炎发生的独立危险因素(P<0.05)。结论高脂血症、胆道系统疾病、TG、ALT是妊娠晚期急性胰腺炎发生的影响因素,临床可针对相关影响因素采取针对性措施。

Objective To analyze the influencing factors for the occurrence of acute pancreatitis during late trimester of pregnancy.Methods A total of 314 pregnant women with 28-30 weeks of pregnancy were divided into two groups of A(complicated with acute pancreatitis,51 cases)and C(without acute pancreatitis,263 cases).The clinical data were analyzed in the two groups.Multivariate logistic regression analysis was applied to analyze the influencing factors for the occurrence of acute pancreatitis during late trimester of pregnancy.Results The proportions of hyperlipidemia and biliary system disease and levels of TG and ALT in group A were higher than those in group C(P<0.05).Multivariate logistic regression analysis showed that having hyperlipidemia or biliary system disease,higher level of TG or ALT were the independent risk factors for the occurrence of acute pancreatitis during late trimester of pregnancy(P<0.05).ConclusionHyperlipidemia,biliary system disease,TG,and ALT are the influencing factors for the occurrence of acute pancreatitis during late trimester of pregnancy,and targeted measures can be taken in clinical practice to address these influencing factors.