浙江省非伤寒沙门菌和副溶血性弧菌急性胃肠炎疾病负担

Burden of acute gastrointestinal illness caused by non-typhoidal Salmonella and Vibrio parahaemolyticus in Zhejiang Province

目的分析浙江省非伤寒沙门菌和副溶血性弧菌引起的急性胃肠炎(AGI)的疾病负担,为食源性疾病防控提供参考。方法通过浙江省食源性疾病监测系统收集2022年非伤寒沙门菌和副溶血性弧菌检出率资料,换算非伤寒沙门菌和副溶血性弧菌AGI发病数、发病率和就诊数,采用伤残调整寿命年(DALY)分析不同年龄组非伤寒沙门菌和副溶血性弧菌AGI的疾病负担。结果2022年浙江省非伤寒沙门菌AGI发病数为88.95万例次,发病率为1352.42/10万,就诊数为32.89万例次,DALY为972.69(95%CI:771.68~1164.16)人年,DALY率为1.48(95%CI:1.17~1.77)/10万;各年龄组中以<5岁组发病率和DALY率最高,分别为3989.51/10万和13.93(95%CI:8.67~18.42)/10万。2022年浙江省副溶血性弧菌AGI发病数为63.94万例次,发病率为972.16/10万,就诊数为16.68万例次,DALY为509.30(95%CI:411.75~699.62)人年,DALY率为0.78(95%CI:0.63~1.06)/10万;各年龄组中以45~<65岁组发病率和DALY率最高,分别为1383.55/10万和1.27(95%CI:1.14~1.96)/10万。结论浙江省非伤寒沙门菌AGI发病率和疾病负担较高;<5岁儿童非伤寒沙门菌AGI和45~<65岁人群副溶血性弧菌AGI需重点监测。

Objective To analyze the disease burden of acute gastrointestinal illness(AGI)caused by non-typhoidal Salmonella and Vibrio Parahaemolyticus in Zhejiang Province,so as to provide the reference for the prevention and control of foodborne diseases.Methods The detection rates of non-typhoidal Salmonella and Vibrio parahaemolyticus in 2022 were collected through the Zhejiang Foodborne Disease Outbreak Surveillance System.The number of cases,incidence and hospitalizations of AGI caused by non-typhoidal Salmonella and Vibrio parahaemolyticus were calculated.Disability adjusted life years(DALY)were used to analyze the disease burden of AGI caused by non-typhoidal Salmonella and Vibrio parahaemolyticus among different age groups.Results The number of AGI cases caused by non-typhoidal Salmonella in Zhejiang Province in 2022 was 889500 person-times,the incidence rate was 1352.42/10^(5),the number of hospital visits was 328900 person-times,the DALY was 972.69(95%CI:771.68-1164.16)person-years,and the DALY rate was 1.48(95%CI:1.17-1.77)/10^(5).The incidence rate and DALY rate were highest in the children aged under 5 years,reaching 3989.51/10^(5)and 13.93(95%CI:8.67-18.42)/10^(5),respectively.The number of AGI cases caused by Vibrio parahaemolyticus in Zhejiang Province was 639400 person-times,the incidence rate of 972.16/10^(5),the number of hospital visits was 166800 person-times,the DALY was 509.30(95%CI:411.75-699.62)person-years,and the DALY rate was 0.78(95%CI:0.63-1.06)/10^(5).The incidence rate and DALY rate were highest in the residents aged 45 to<65 years,reaching 1383.55/10^(5)and 1.27(95%CI:1.14-1.96)/10^(5),respectively.Conclusions The incidence and DALY of AGI caused by non-typhoidal Salmonella were relatively high in Zhejiang Province.The AGI caused by non-typhoidal Salmonella in the children under 5 years and the AGI caused by Vibrio parahaemolyticus in the residents aged 45 to<65 years need to be monitored with priority.