我国中老年慢性病患者共病网络与模式分析

Network and Patterns of Multimorbidity among Middle-aged and Elderly Patients with Chronic Diseases in China

目的:探讨我国中老年慢性病患者的共病模式及网络,为慢性病共病的管理提供参考。方法:利用2020年中国健康与养老追踪调查(China Health and Retirement Longitudinal Study,CHARLS)数据,选取≥45岁的慢性病患者为研究对象,运用Gephi软件对其共患网络进行分析。结果:我国中老年慢性病患者慢性病共患率为72.71%,女性共患率高于男性(73.42%和70.74%,χ^(2)=13.789,P<0.001);共病组合以二元与三元最为常见,二元共病组合中胃部或消化系统疾病+关节炎或风湿病(14.58%)患病率最高,三元共病组合中高血压+关节炎或风湿病+胃部或消化系统疾病(6.65%)患病率最高;慢性病患者共病网络以高血压为中心,与关节炎或风湿病之间的联系最紧密。结论:我国中老年慢性病患者共患率高,高血压+关节炎或风湿病等共病模式典型,不同人群慢性病共患情况存在差异。因此,需要针对不同群体特征,制定个性化、精准化的慢性病共病防控策略,有针对性地对关键慢性病进行防控。

Objective:To explore multimorbidity network and patterns in middle-aged and elderly patients with chronic diseases,and to provide references for the management of multimorbidity in this population.Methods:Using data from the China Health and Retirement Longitudinal Study(CHARLS)2020,patients aged≥45 years with chronic diseases were selected,Gephi was used to analyze the multiple chronic network.Results:The participates suffering from 2 or more chronie diseases accounted for 72.71%,female had higher prevalence of multimorbidity than male(73.42%and 70.74%,χ^(2)=13.789,P<0.001).The most common comorbidity combinations were two and three chronic diseases coexisted.Stomach or other digestive diseases&arthritis o rheumatism(14.58%)was the top 1 pair pattern of 2 kinds of diseases combination.Hypertension&arthritis or rheumatism&stomach or other digestive diseases(6.65%)was the top 1 pattern of 3 kinds of diseases combination.Hypertension was the key diseases on the network of multimorbidity,with the strongest association with arthritis or rheumatism.Conclusion:There was a high prevalence of multimorbidity among middle-aged and elderly patients with chronie diseases in China,hypertension&arthritis or rheumatism was the most typical pattern of multimorbidity.Thus,more personalized and accurate strategies should be developed to prevent and control key chronic diseases according to characteristics of different groups.