冠状动脉扩张症患者焦虑、抑郁和用药依从性相关分析

Correlation analysis of anxiety,depression and drug compliance in patients with coronary artery ectasia

目的开展冠状动脉扩张症患者焦虑、抑郁和用药依从性状况的调查及影响因素,分析其用药依从性与焦虑抑郁之间的关系。方法回顾性调查了2020年3月~2022年9月河北省某三级甲等综合医院心内科的98名冠状动脉扩张症患者。采用一般资料问卷,综合医院焦虑抑郁量表(HAD),Morisky用药依从性量表(MMAS-8)进行问卷调查。结果冠状动脉扩张症患者HAD得分为(9.51±4.77),MMAS-8得分为(5.46±1.46)。Spearman秩相关分析冠状动脉扩张症患者的用药依从性与焦虑抑郁呈负相关(r=-0.608,P<0.01)。多元线性逐步回归分析显示,家庭人均月收入,糖尿病,BMI,陪护类型是CAE患者焦虑抑郁的主要影响因素(P<0.05)。结论冠状动脉扩张症患者焦虑抑郁水平较高,用药依从性较差,二者呈负相关。

Objective To conduct a survey on the current status of anxiety and depression in patients with coronary artery ectasia(CAE)and analysis of the influencing factors,and to analyze the relationship between their compliance with secondary prevention medication and anxiety,depression.Methods Ninety-eight patients diagnosed with CAE by coronary angiography in the cardiology department of a tertiary care general hospital in Hebei Province from March 2020 to September 2022 were retrospectively investigated.General information questionnaires,the Hospital Anxiety and Depression Scale(HAD),and the Morisky Medication Adherence Scale-8(MMAS-8)were used to conduct the questionnaire survey.Results HAD scores of CAE patients were(9.51±4.77)and MMAS-8 scores were(5.46±1.46).Spearman rank correlation analysis showed Medication adherence in patients with CAE was negatively correlated with anxiety and depression(r=-0.608,P<0.01).Multiple linear stepwise regression analysis showed that monthly per capita household income,diabetes,BMI,and type of companionship were the main influencing factors of anxiety and depression in CAE patients(P<0.05).Conclusion The level of anxiety and depression in patients with coronary artery dilatation was higher,and the compliance with secondary prophylactic drugs was poor,which showed a negative correlation.