控制营养状况评分与糖尿病足溃疡创面修复的相关性研究

Correlation between the Controlling Nutritional Status score and wound repair of diabetic foot ulcer

目的探讨控制营养状况(COUNT)评分与糖尿病足溃疡(DFU)创面修复的相关性。方法随机选取2019年11月20日—2022年11月20日在本院接受治疗的80例DFU患者为研究对象,根据创面修复情况的不同分为非创面修复组(n=47)和创面修复组(n=33)。记录创面修复与住院时间,比较创面修复组与非创面修复组的临床特征及CONUT评分,采用多因素Logistic回归模型分析DFU创面修复的影响因素。结果非创面修复组患者的住院时间是16.00(10.50,24.00)d,短于创面修复组患者的44.00(31.00,61.80)d,差异有统计学意义(P<0.05)。非创面修复组患者的总胆固醇(TC)、踝肱指数(ABI)、CONUT评分以及营养不良比率均高于创面修复组,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,CONUT评分、营养不良、TC、ABI是DFU创面修复的独立危险因素(P<0.05)。结论DFU患者的营养不良、ABI、TC和CONUT评分均会对其创面修复造成不利影响,而CONUT评分可以准确预测患者的创面修复风险,可以作为临床医生早期评估DFU的可靠参考依据。

Objective To investigate the correlation between the Controlling Nutritional Status(CONUT)score and wound repair of diabetic foot ulcer(DFU).Methods A total of 80 DFU patients treated in the Hospital from November 20,2019 to November 20,2022 were randomly selected as the study objects and divided into non-wound repair group(n=47)and wound repair group(n=33)based on wound repair status.Wound repair and hospital stay were recorded;clinical characteristics and the CONUT score were compared between the wound repair group and the non-wound repair group;the influencing factors of DFU wound repair were analyzed by the multivariate Logistic regression model.Results The hospital stay of patients in the non-wound repair group was 16.00(10.50 to 24.00)days,which was significantly shorter than 44.00(31.00 to 61.80)days of patients in the wound repair group(P<0.05).The total cholesterol(TC),ankle-brachial index(ABI),the CONUT score,and malnutrition rate of patients in the non-wound repair group were significantly higher than those in the wound repair group(P<0.05).The results of multivariate Logistic regression analysis showed that the CONUT score,malnutrition,TC and ABI were the independent risk factors for wound repair of DFU(P<0.05).Conclusion Malnutrition,ABI,TC and CONUT score in DFU patients can adversely affect wound repair,and the CONUT score can accurately predict the risk of wound repair in patients,serving as a reliable reference for clinicians in early assessment of DFU.