康复训练联合鼠神经生长因子治疗小儿脑瘫的临床效果观察

Clinical Observation of Rehabilitation Training Combined with Rat Nerve Growth Factor in the Treatment of Pediatric Cerebral Palsy

目的探讨康复训练联合鼠神经生长因子在小儿脑瘫临床治疗中的应用效果。方法选取本院2021年1月至2023年10月收治的291例小儿痉挛型脑瘫患儿作为研究对象,应用随机数字表法分为观察组(康复训练联合鼠神经生长因子,146例)和对照组(康复训练,145例),对比两组脑功能康复情况、S-S语言发育情况。结果治疗后,观察组患儿的粗大运动功能评估量表(GMFM)评分、0~6岁小儿神经心理发育量表发育商(DQ)评分比对照组高(P<0.05),观察组Ashworth量表评分比对照组低(P<0.05)。观察组语言发育低于实际年龄≥3个阶段、低于实际年龄≥2个阶段的患儿比例比对照组更低,语言发育低于实际年龄≥1个阶段的患儿比例比对照组更高(P<0.05)。结论在小儿脑瘫的临床治疗中,实施康复训练的基础上应用鼠神经生长因子进行治疗能够让患儿的脑功能得到更好的恢复,促进语言发育。

Objective To evaluate the efficacy of rehabilitation training combined with rat nerve growth factor in the clinical treatment of pediatric cerebral palsy.Methods A total of 291 children with spastic cerebral palsy admitted to the hospital from January 2021 to October 2023 were taken as the research objects.By using random number table method,they were divided into observation group(rehabilitation training combined with rat nerve growth factor,146 cases),and control group(rehabilitation training,145 cases),and the brain function rehabilitation and S-S language development of the two groups were compared.Results After the treatment,Crude motor function assessment scale(GMFM)score,developmental quotient(DQ)score compared with the control group are higher(P<0.05),the Ashworth scale score of observation group is lower than the control score(P<0.05).The proportion of children in the observation group with language development that is more than 3 stages below their actual age,and more than 2 stages below their actual age,is lower than that of the control group.The proportion of children with language development that is more than 1 stage below their actual age is higher than that of the control group(P<0.05).Conclusions In the clinical treatment of pediatric cerebral palsy,on the basis of rehabilitation training,the application of rat nerve growth factor can make the brain function of children get better recovery.