输尿管软镜碎石术后患者发生并发症的影响因素分析

Analysis of influencing factors of complications in patients after flexible ureteroscopic lithotripsy

目的分析输尿管软镜碎石术(FURL)后患者发生并发症的影响因素。方法回顾性分析接受FURL治疗的278例肾结石患者的临床资料,依据术后是否发生并发症分为并发症组和非并发症组。采用多因素Logistic回归分析探讨FURL术后患者发生并发症的影响因素。结果FURL术后,51例发生并发症,227例未发生并发症。单因素分析结果显示,两组的糖尿病、输尿管狭窄、结石直径、术前尿培养、手术时间比较,差异具有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,糖尿病、输尿管狭窄、结石直径、术前尿培养、手术时间是FURL术后发生并发症的影响因素(P<0.05)。结论糖尿病、输尿管狭窄、结石直径≥2 cm、术前尿培养阳性、手术时间≥90 min是导致FURL术后发生并发症的影响因素,临床医师应高度重视以上影响因素,并采取合理的预防措施以减少术后并发症。

Objective To analyze the influencing factors of complications in patients after flexible ureteroscope lithotripsy(FURL).Methods The clinical data of 278 patients with renal calculi treated with FURL were retrospectively analyzed,and the patients were divided into complication group and non-complication group according to whether postoperative complications occurred.Multivariate Logistic regression analysis was used to explore the influencing factors of complications in patients after FURL.Results After FURL,51 cases had complications and 227 cases had no complications.Univariate analysis showed that there were significant differences in diabetes,ureteral stricture,stone diameter,preoperative urine culture and operation time between the two groups(P<0.05).Multivariate Logistic regression analysis showed that diabetes,ureteral stricture,stone diameter,preoperative urine culture and operation time were influencing factors of complications after FURL(P<0.05).Conclusion Diabetes,ureteral stricture,stone diameter≥2 cm,positive preoperative urine culture and operation time≥90 min are independent influencing factors for complications after FURL,and clinicians should attach great importance to the above factors and take reasonable preventive measures to reduce postoperative complications.