摘要
目的:探究低剂量碘海醇在肺动脉栓塞患者多层螺旋CT诊断中的价值。方法:选取2023年1月—2024年1月我院收治的68例肺动脉栓塞患者,且行多层螺旋CT诊断。对所有患者应用抽签法进行分组,包括参照组(34例)、研究组(34例)。参照组患者应用高剂量碘海醇,即碘浓度是350 mgI/ml,研究组患者应用低剂量碘海醇,即碘浓度300mgI/ml。比较两组重建图像质量、静脉污染评分、动脉CT值、信噪比(SNR)、对比信噪比(CNR)、肾功能指标。结果:研究组静脉污染评分低于参照组(P<0.05),而两组图像质量评分比较,差异无统计学意义(P>0.05)。两组主肺动脉、肺叶动脉、右肺动脉、左肺动脉CT值比较,差异无统计学意义(P>0.05);研究组SNR、CNR低于参照组(P<0.05);研究组检查后48 h的Cre、BUA、BUN、MA低于参照组(P<0.05)。结论:肺动脉栓塞患者多层螺旋CT诊断中应用低剂量碘海醇能降低静脉污染,减轻肾损伤,且不影响图像质量,值得临床应用。
Objective:To explore the value of low-dose iohexol in the diagnosis of multi-slice spiral CT in patients with pulmonary embolism.Methods:Sixty-eight patients with pulmonary embolism admitted to our hospital from January 2023 to January 2024 were selected and diagnosed by multi-slice spiral CT.All patients were grouped by lottery,including the reference group(34 patients)and the study group(34 patients).The patients in the reference group were treated with high-dose iohexol,that was,the iodine concentration was 350 mgI/mL,and the patients in the study group were treated with low-dose iohexol,that was,the iodine concentration was 300 mgI/mL.The reconstructed image quality,venous contamination score,arterial CT value,signal-to-noise ratio(SNR),contrast-tonoise ratio(CNR)and renal function indexes were compared between the two groups.Results:The venous pollution score of the study group was lower than that of the reference group(P<0.05);There was no difference in image quality scores between the two groups(P>0.05).There was no significant difference in CT values of main pulmonary artery,pulmonary lobe artery,right pulmonary artery and left pulmonary artery between the two groups(P>0.05).The SNR and CNR of the study group were lower than those of the reference group(P<0.05).The Cre,BUA,BUN and MA of the study group at 48 h after examination were lower than those of the reference group(P<0.05).Conclusion:The application of low-dose iohexol in the diagnosis of multi-slice spiral CT in patients with pulmonary embolism can reduce venous pollution,reduce renal injury,and do not affect the image quality,which is worthy of clinical application.
作者
黄枫林
郑晓娜
高兴军
HUANG Fenglin;ZHENG Xiaona;GAO Xingjun(Department of CT Diagnosis,Xinyang Central Hospital,Xinyang 464000,Henan,China)
出处
《中国药物滥用防治杂志》
CAS
2024年第8期1479-1482,共4页
Chinese Journal of Drug Abuse Prevention and Treatment
基金
山西省高等学校科技创新项目和哲学社会科学研究项目(编号:201804031)。