不同剂量碘海醇在肺动脉栓塞患者多层螺旋CT诊断中的效果对比

Comparison of the Effects of Different Doses of Iohexol in the Diagnosis of Multi-slice Spiral CT in Patients with Pulmonary Embolism

目的:探究低剂量碘海醇在肺动脉栓塞患者多层螺旋CT诊断中的价值。方法:选取2023年1月—2024年1月我院收治的68例肺动脉栓塞患者,且行多层螺旋CT诊断。对所有患者应用抽签法进行分组,包括参照组(34例)、研究组(34例)。参照组患者应用高剂量碘海醇,即碘浓度是350 mgI/ml,研究组患者应用低剂量碘海醇,即碘浓度300mgI/ml。比较两组重建图像质量、静脉污染评分、动脉CT值、信噪比(SNR)、对比信噪比(CNR)、肾功能指标。结果:研究组静脉污染评分低于参照组(P<0.05),而两组图像质量评分比较,差异无统计学意义(P>0.05)。两组主肺动脉、肺叶动脉、右肺动脉、左肺动脉CT值比较,差异无统计学意义(P>0.05);研究组SNR、CNR低于参照组(P<0.05);研究组检查后48 h的Cre、BUA、BUN、MA低于参照组(P<0.05)。结论:肺动脉栓塞患者多层螺旋CT诊断中应用低剂量碘海醇能降低静脉污染,减轻肾损伤,且不影响图像质量,值得临床应用。

Objective:To explore the value of low-dose iohexol in the diagnosis of multi-slice spiral CT in patients with pulmonary embolism.Methods:Sixty-eight patients with pulmonary embolism admitted to our hospital from January 2023 to January 2024 were selected and diagnosed by multi-slice spiral CT.All patients were grouped by lottery,including the reference group(34 patients)and the study group(34 patients).The patients in the reference group were treated with high-dose iohexol,that was,the iodine concentration was 350 mgI/mL,and the patients in the study group were treated with low-dose iohexol,that was,the iodine concentration was 300 mgI/mL.The reconstructed image quality,venous contamination score,arterial CT value,signal-to-noise ratio(SNR),contrast-tonoise ratio(CNR)and renal function indexes were compared between the two groups.Results:The venous pollution score of the study group was lower than that of the reference group(P<0.05);There was no difference in image quality scores between the two groups(P>0.05).There was no significant difference in CT values of main pulmonary artery,pulmonary lobe artery,right pulmonary artery and left pulmonary artery between the two groups(P>0.05).The SNR and CNR of the study group were lower than those of the reference group(P<0.05).The Cre,BUA,BUN and MA of the study group at 48 h after examination were lower than those of the reference group(P<0.05).Conclusion:The application of low-dose iohexol in the diagnosis of multi-slice spiral CT in patients with pulmonary embolism can reduce venous pollution,reduce renal injury,and do not affect the image quality,which is worthy of clinical application.