鼻呼出气一氧化氮检测在儿童原发性纤毛运动障碍中的诊断应用

Diagnostic application of nasal nitric oxide detection in primary ciliary dyskinesia in children

原发性纤毛运动障碍是一组源于气道的遗传异质性疾病,临床表现多样,诊断方式复杂,目前尚无公认的诊断金标准。鼻部一氧化氮检测与其他检查方式相比,操作简单且无创,价格相对低廉,越来越多地应用于儿童原发性纤毛运动障碍的筛查。该文主要探讨鼻部一氧化氮检测在儿童原发性纤毛运动障碍中的诊断应用。

Primary ciliary dyskinesia is a group of genetic heterogeneous diseases originating from the airway.It has various clinical manifestations with complex diagnostic methods,and there is no recognized gold standard for diagnosis at present.Compared with other examination methods,the detection of nasal nitric oxide is simple and non-invasive,and the price is relatively low.It is used more and more in the screening of primary ciliary dyskinesia in children.This paper mainly discusses the application of nasal nitric oxide detection in the diagnosis of primary ciliary dyskinesia in children.