氨基糖苷类药物光电化学传感器的构建及应用研究进展

Research progress on construction and application of aminoglycosides optical and electrochemical sensors

氨基糖苷类药物(aminoglycosides,AGs)残留严重危害人体健康,传统检测方法操作复杂、成本高昂,光学和电化学传感器灵敏度高、特异性强、操作简单且成本低,应用前景广阔。该文介绍了食品中AGs光学与电化学传感器的构建方法与研究进展,涉及荧光法、化学发光法、比色法、表面增强拉曼光谱、电致发光及电化学方法。最后总结了不同类别传感器的优势与挑战,为新型光电化学传感器的构建与应用提供了新的思路,为该类药物的安全监控提供了技术支持。

The residues of aminoglycosides(AGs)are seriously harmful to human health.Conventional detection methods have the defects of complicated operations and high cost.Optical and electrochemical sensors possess high sensitivity,strong specificity,simple operation,low cost,and extensive application prospects.This article introduced the latest construction,application and research advances in optical and electrochemical sensors for the detection of AGs in foods,involving fluorescence,chemiluminescence,colorimetry,surface-enhanced Raman spectroscopy,electroluminescence,and electrochemistry methods.Finally,this review summarized the advantages and challenges of different types of sensors and provided new thinking for the construction and application of AGs optical and electrochemical sensors.Additionally,it provided technical support for the safety monitoring of such drugs.