剖宫产术后静脉血栓栓塞危险因素分析

Analysis of risk factors for venous thromboembolism after cesarean section

目的 探讨剖宫产术后静脉血栓栓塞的危险因素。方法 选取2022年1月至2023年12月慈利县妇幼保健院产科收治的90例剖宫产术后静脉血栓栓塞产妇作为研究对象,随机选取150例同期剖宫产术后未发生静脉血栓栓塞的产妇作为对照组。单因素分析两组高龄(≥35岁)、孕期增重、反复流产频次(≥2次)、辅助性生殖技术、双胎妊娠、子痫前期、妊娠糖尿病、前置胎盘、产后输血、产后出血量(≥1000 ml)情况,多因素logistic回归分析剖宫产术后静脉血栓栓塞发生的独立危险因素。结果 两组高龄(≥35岁)、孕期增重、反复流产频次(≥2次)、辅助性生殖技术、子痫前期、产后输血、产后出血量(≥1000ml)比较,差异有统计学意义(P <0.05)。多因素logistic回归分析显示,高龄(≥35岁)、孕期增重(过多)、反复流产频次(≥2次)、辅助性生殖技术、子痫前期、产后输血、产后出血量(≥1000ml)是剖宫产术后静脉血栓栓塞发生的独立危险因素(P <0.05)。结论 高龄(≥35岁)、孕期增重(过多)、反复流产频次(≥2次)、辅助性生殖技术、子痫前期、产后输血、产后出血量(≥1000ml)会增加剖宫产术后静脉血栓栓塞的发生风险,应加强风险因素的监测和预防,减少剖宫产术后静脉血栓栓塞的发生。

Objective To explore the risk factors for venous thromboembolism(VTE)after cesarean section.Methods A total of 90 parturients with VTE after cesarean section admitted to Maternal and Child Health Hospital in Cili County from January 2022 to December 2023 were selected as the study objects.And 150 parturients who underwent cesarean section without VTE during the same period were randomly selected as the control group.Univariate analysis was performed on advanced age(≥35 years old),gestational weight gain,frequency of recurrent miscarriages(≥2 times),assisted reproductive technology,twin pregnancy,preeclampsia,gestational diabetes mellitus,placenta previa,postpartum blood transfusion,and postpartum hemorrhage(≥1000 ml).Multivariate logistic regression analysis was performed to identify independent risk factors for VTE after cesarean section.Results There were statistically significant differences in advanced age(≥35 years old),gestational weight gain,frequency of recurrent miscarriages(≥2 times),assisted reproductive technology,preeclampsia,postpartum blood transfusion,and postpartum hemorrhage(≥1000 ml)between the two groups(P<0.05).Multivariate logistic regression analysis showed that advanced age(≥35 years old),gestational weight gain(excessive),frequency of recurrent miscarriages(≥2 times),assisted reproductive technology,preeclampsia,postpartum blood transfusion,and postpartum hemorrhage(≥1000 ml)were the independent risk factors for VTE(P<0.05).Conclusion Advanced age(≥35 years old),gestational weight gain(excessive),frequency of recurrent miscarriages(≥2 times),assisted reproductive technology,preeclampsia,postpartum blood transfusion,and postpartum hemorrhage(≥1000 ml)can increase the risk of VTE after cesarean section.It is necessary to strengthen the monitoring and prevention of risk factors to reduce the incidence of VTE after cesarean section.