肠壁囊样积气症25例临床分析

Pneumatosis cystoides intestinalis:report of 25 cases

目的探讨肠壁囊样积气症(PCI)患者的临床特征、治疗及预后。方法回顾性分析2011年1月至2020年12月北京大学人民医院诊治的25例PCI患者的临床资料。结果本组25例PCI患者中男9例,女16例,中位年龄69(55~78)岁,无症状者6例,其余患者主诉以腹痛多见(12例),其次为腹泻(4例)、便秘(2例)、腹胀(1例),15例PCI患者合并低白蛋白血症。PCI以肠壁内多发囊状气体积聚为主要影像学表现,23例发生于结直肠,17例合并腹腔游离气体。所有患者均通过保守治疗治愈,随访至今未发现与PCI相关的死亡病例。结论PCI是一种罕见的消化道疾病,临床表现不典型,保守治疗是其有效的治疗措施,预后良好。

ObjectiveTo explore the clinical features,treatment and prognosis of patients with pneumatosis cystoides intestinalis(PCI).MethodsThe clinical data of 25 PCI patients at Peking University People's Hospital admitted from Jan 2011 to Dec 2020 were retrospectively analyzed.ResultsAmong these 25 PCI patients,there were 9 males and 16 females with a median age of 69(55-78)years.Six patients were asymptomatic,while the main complaint of the remaining patients was abdominal pain(12 cases),followed by diarrhea(4 cases),constipation(2 cases),and abdominal distension(1 case).Fifteen patients with PCI also had hypoalbuminemia.The main radiological manifestation of PCI was the presence of multiple gas-filled cysts within the intestinal wall,with 23 cases occurring in the colon and 17 cases combined with free intra-abdominal gas.All patients were cured with conservative treatment,with no PCI-related deaths during follow-up.ConclusionsPCI is a rare gastrointestinal disease with atypical clinical manifestations.Conservative management is an effective treatment with good prognosis.