妊娠期糖尿病患者血糖水平与新生儿结局的相关性及其临床意义

Correlation Between Blood Glucose Level and Neonatal Outcome in Patients with Gestational Diabetes Mellitus and its Clinical Significance

目的研究妊娠期糖尿病(GDM)患者血糖水平与新生儿结局的相关性及其临床意义。方法以2020年1月-2023年1月寻乌县人民医院接收的60例GDM患者为研究对象,依据其产前血糖控制情况分为血糖控制组(36例)与血糖异常组(24例),比较两组产妇妊娠结局、新生儿胎龄、Apgar评分及新生儿结局,分析产妇血糖水平与新生儿结局的相关性。结果血糖异常组不良妊娠结局发生率高于血糖控制组(P<0.05);血糖异常组新生儿胎龄、Apgar评分小于血糖控制组(P<0.05);血糖异常组不良新生儿结局发生率高于血糖控制组(P<0.05)。Spearman相关性分析显示,GDM产妇不良新生儿结局(巨大儿、低血糖、呼吸窘迫综合征、低血压)风险与其血糖异常水平呈正相关(P<0.05)。结论GDM患者的血糖水平与其新生儿结局具有确切相关性,其血糖水平越高,不良新生儿结局的发生风险越高。

Objective To study the correlation between blood glucose level and neonatal outcome in patients with gestational diabetes mellitus(GDM)and its clinical significance.Methods A total of 60 GDM patients received in Xunwu County People's Hospital from January 2020 to January 2023 were selected as the research objects.According to their prenatal blood glucose control,they were divided into blood glucose control group(36 patients)and abnormal blood glucose group(24 patients).The pregnancy outcome,neonatal gestational age,Apgar score and neonatal outcome of the two groups were compared,and the correlation between maternal blood glucose level and neonatal outcome was analyzed.Results The incidence of adverse pregnancy outcomes in the abnormal blood glucose group was higher than that in the blood glucose control group(P<0.05).The gestational age and Apgar score of neonates in the abnormal blood glucose group were lower than those in the blood glucose control group(P<0.05).The incidence of adverse neonatal outcomes in the abnormal blood glucose group was higher than that in the blood glucose control group(P<0.05).Spearman correlation analysis showed that the risk of adverse neonatal outcomes(giant infant,hypoglycemia,respiratory distress syndrome,hypotension)in GDM women was positively correlated with their abnormal blood glucose levels(P<0.05).Conclusion The blood glucose level of GDM patients has a definite correlation with their neonatal outcomes.The higher the blood glucose level,the higher the risk of adverse neonatal outcomes.