人感染猪链球菌致听力障碍1例并文献复习

Hearing impairment caused by Streptococcus suis infection:A case report and literature review

目的通过报道人感染猪链球菌致化脓性脑膜炎并发双耳重度混合性听力障碍1例的临床表现、诊疗过程、疾病转归及预后,为临床诊治该病提供参考。方法分析1例人感染猪链球菌致化脓性脑膜炎患者的临床表现、病原学检查、诊治过程及并发症处理,对相关文献进行复习。结果该患者中年男性,以发热、畏寒、头痛起病,急性起病、进展迅速,于2021年11月13日入海南医科大学第二附属医院,诊断为化脓性脑膜炎、脓毒症、突发性混合性听力障碍,经过积极治疗后患者病情好转出院,但仍遗留双耳重度混合性听力障碍、左侧鼓膜穿孔。结论人感染猪链球菌病起病急骤,进展迅速,早期确诊及使用足量地塞米松联合敏感抗生素等积极对症治疗,可能是治疗人感染猪链球菌致化脓性脑膜炎并发听力障碍的有效方法。

Objective To report the clinical manifestations,diagnosis and treatment of a case of human Streptococcus suis(S.S)purulent meningitis complicated with bilateral severe mixed hearing impairment,and improve the prognosis of the patient,and provide reference for clinical diagnosis and treatment of the disease.Method The clinical manifestations,etiological examination,diagnosis and treatment process and complications of a case of Streptococcus suis purulent meningitis were analyzed,and the relevant literature was reviewed.Results The patient was a middle⁃aged man with fever,chills and headache.Acute onset and rapid progression.The patient was admitted to the Second Affiliated Hospital of Hainan Medical University on November 13,2021.And was diagnosed as suppurative meningitis,sepsis and sudden mixed hearing impairment.After active treatment,the patient's condition improved and discharged,but still left severe mixed hearing impairment and perforation of left tympanic membrane.Conclusions The onset of human infection with Streptococcus suis disease was sudden and the progressed rapidly.Early diagnosis and active symptomatic treatment of sufficient dexamethasone combined with sensitive antibiotics might be an effective method to treat human infection with Streptococcus suis purulent meningitis.