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生育信息支持对育龄期癌症病人生育忧虑干预效果的Meta分析

Effect of fertility information support on reproductive concerns in cancer patients of childbearing age:a Meta-analysis
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摘要 目的:系统评价生育信息支持对育龄期癌症病人生育忧虑水平的影响。方法:系统检索PubMed、EMbase、the Cochrane Library、CINAHL、Web of Science、中国知网、维普数据库、万方数据库、中国生物医学文献数据库中关于生育信息支持对育龄期癌症病人生育忧虑影响的随机对照试验与类试验研究,检索时限为建库至2023年4月,使用RevMan 5.4软件进行Meta分析。结果:共纳入10篇文献,其中,随机对照试验7篇,类试验3篇,涉及883例病人。Meta分析结果显示,生育信息支持能增加育龄期癌症病人的生育知识[SMD=0.27,95%CI(0.10,0.44),P=0.002],减轻生育忧虑[SMD=-2.23,95%CI(-3.21,-1.26),P<0.00001],改善生育相关决策冲突[MD=-9.85,95%CI(-13.27,-6.44),P<0.00001],但对减轻育龄期癌症病人生育相关决策后悔的效果有限。结论:生育信息支持有助于提高育龄期癌症病人的生育知识,降低病人的生育忧虑水平、生育相关决策冲突。 Objective:To systematically evaluate the effects of fertility information support on fertility anxiety in cancer patients of childbearing age.Methods:Randomized controlled trials and quasi trial studies on the effects of fertility information support on fertility anxiety in cancer patients of childbearing age were retrieved from PubMed,EMbase,the Cochrane Library,CINAHL,Web of Science,CNKI,VIP,WanFang Database and CBM.The search period was from the establishment of the database to April 2023,and RevMan 5.4 software was used for Meta-analysis.Results:A total of 10 articles were included,including 7 randomized controlled trials and 3 quasi trial studies,involving 883 patients.The results of Meta-analysis showed that fertility information support can increase reproductive knowledge(SMD=0.27,95%CI 0.10-0.44,P=0.002),alleviate reproductive anxiety(SMD=-2.23,95%CI-3.21--1.26,P<0.00001),and improve childbearing decision-making conflicts in cancer patients of reproductive age(MD=-9.85,95%CI-13.27--6.44,P<0.00001),but the effect of reducing childbearing decision-making regret is limited.Conclusion:Fertility information support can improve the fertility knowledge of cancer patients of childbearing age,reduce the level of fertility anxiety and the conflict of childbearing decision.
作者 韩露 李金花 肖羽乔 刘佳惠 魏涛 陈婕君 HAN Lu;LI Jinhua;XIAO Yuqiao;LIU Jiahui;WEI Tao;CHEN Jiejun(School of Nursing,Hunan University of Chinese Medicine,Hunan 410000 China)
出处 《循证护理》 2024年第18期3265-3272,共8页 Chinese Evidence-Based Nursing
基金 湖南省卫生健康委2024年度科研课题,编号:W20243207。
关键词 生育信息支持 癌症病人 生育忧虑 育龄期 循证护理 META分析 fertility information support cancer patients fertility anxiety childbearing age evidence-based nursing Meta-analysis
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