摘要
目的本研究通过meta分析评估经皮内镜椎间孔入路微创手术(PETFA)治疗腰椎间盘突出症的疗效,为临床提供科学依据。方法检索PubMed、EMbase、Web of Science、CNKI和万方数据库,筛选随机对照试验(RCTs),使用Rev Man 5.3软件,采用相对风险(RR)和标准化平均差异(SMD)进行统计。结果纳入8篇高质量研究,涉及462例患者。结果显示PETFA手术的多项指标均优于传统手术,包括更短的手术时间[平均差(MD)=-6.51],较少的术中出血(MD=-7.09),更短的住院时间(MD=-2.85),以及更佳的术后疼痛缓解(MD=-1.68)和功能恢复(MD=-0.89)。结论PETFA微创手术在治疗腰椎间盘突出症方面具显著优势,推荐在临床中广泛应用。
【Objective】Using a meta-analysis to evaluate the effectiveness of percutaneous endoscopic transforaminal lumbar discectomy(PETFA)in treating lumbar disc herniation,inorder to provide a scientific basis for clinical practice.【Methods】We searched databases such as PubMed,EMbase,Web of Science,CNKI,and Wanfang,selecting randomized controlled trials(RCTs).Statistical analyses were conducted using RevMan 5.3 software,employing relative risk(RR)and standardized mean difference(SMD).【Results】Eight high-quality studies involving 462 patients were included.The findings demonstrate that PETFA surgery significantly outperforms traditional surgery in various metrics,including shorter surgery duration(MD=−6.51),reduced intraoperative blood loss(MD=−7.09),shorter hospital stays(MD=−2.85),improved postoperative pain relief(MD=−1.68),and enhanced functional recovery(MD=−0.89).【Conclusion】PETFA minimally invasive surgery exhibits significant advantages in treating lumbar disc herniation,making it highly recommended for widespread clinical use.
作者
廖子坤
夏暑阳
陶晖
张平
LIAO Zikun;XIA Shuyang;TAO Hui;ZHANG Ping(Department of Spine Surgery,The Third Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510150,China;Guangdong Provincial Key Laboratory of Major Obstetric Diseases,Guangzhou,Guangdong 510150,China;Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology,Guangzhou,Guangdong 510150,China;Department of Clinical Medicine,Anhui Medical University,Hefei,Anhui 230032,China;Department of Spine Surgery,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230000,China)
出处
《中国医学工程》
2024年第9期29-35,共7页
China Medical Engineering
基金
广州市科技局市校(院)联合资助项目(202201020211)。
关键词
腰椎间盘突出症
经皮椎间孔镜
微创手术
META分析
lumbar disc herniation
percutaneous endoscopic transforaminal approach
minimally invasive surgery
metaanalysis