经皮内镜椎间孔入路微创治疗腰椎间盘突出症疗效的meta分析

Meta-analysis of percutaneous endoscopic transforaminal lumbar discectomy in curative effect of minimally invasive treatment of lumbar disc herniation

目的本研究通过meta分析评估经皮内镜椎间孔入路微创手术(PETFA)治疗腰椎间盘突出症的疗效,为临床提供科学依据。方法检索PubMed、EMbase、Web of Science、CNKI和万方数据库,筛选随机对照试验(RCTs),使用Rev Man 5.3软件,采用相对风险(RR)和标准化平均差异(SMD)进行统计。结果纳入8篇高质量研究,涉及462例患者。结果显示PETFA手术的多项指标均优于传统手术,包括更短的手术时间[平均差(MD)=-6.51],较少的术中出血(MD=-7.09),更短的住院时间(MD=-2.85),以及更佳的术后疼痛缓解(MD=-1.68)和功能恢复(MD=-0.89)。结论PETFA微创手术在治疗腰椎间盘突出症方面具显著优势,推荐在临床中广泛应用。

【Objective】Using a meta-analysis to evaluate the effectiveness of percutaneous endoscopic transforaminal lumbar discectomy(PETFA)in treating lumbar disc herniation,inorder to provide a scientific basis for clinical practice.【Methods】We searched databases such as PubMed,EMbase,Web of Science,CNKI,and Wanfang,selecting randomized controlled trials(RCTs).Statistical analyses were conducted using RevMan 5.3 software,employing relative risk(RR)and standardized mean difference(SMD).【Results】Eight high-quality studies involving 462 patients were included.The findings demonstrate that PETFA surgery significantly outperforms traditional surgery in various metrics,including shorter surgery duration(MD=−6.51),reduced intraoperative blood loss(MD=−7.09),shorter hospital stays(MD=−2.85),improved postoperative pain relief(MD=−1.68),and enhanced functional recovery(MD=−0.89).【Conclusion】PETFA minimally invasive surgery exhibits significant advantages in treating lumbar disc herniation,making it highly recommended for widespread clinical use.