喜炎平注射液治疗小儿轮状病毒性肠炎的疗效及治疗策略分析

Efficacy and Treatment Strategy of Xiyanping Injection in the Treatment of Pediatric Rotavirus Enteritis

目的 探究喜炎平注射液运用于小儿轮状病毒性肠炎中的临床治疗效果。方法 选取2021年2月—2022年8月商河县中医医院收治的94例小儿轮状病毒性肠炎患儿为研究对象,根据不同的治疗方法分为对照组(47例,接受常规药物治疗干预)和观察组(47例,在对照组的基础上接受喜炎平注射液药物治疗干预)。比较两组临床疗效、炎症因子水平(白细胞介素6、C反应蛋白、降钙素原)、临床相关症状。结果 观察组治疗总有效率为97.87%(46/47),高于对照组的85.11%(40/47),差异有统计学意义(χ^(2)=4.919,P=0.027)。治疗后,两组炎症因子水平、退热时间以及病毒转阴时间等指标均改善,且观察组优于对照组,差异有统计学意义(P均<0.05)。观察组不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论 临床在小儿轮状病毒性肠炎治疗中应用喜炎平注射液药物,有利于改善患儿的临床症状,降低其炎症因子水平,从而提高疗效,促进疾病恢复。

Objective To investigate the clinical therapeutic effect of Xiyanping Injection in pediatric rotavirus enteritis.Methods A total of 94 cases of pediatric rotavirus enteritis admitted to Shanghe Hospital of Traditional Chinese Medicine from February 2021 to August 2022 were selected as the research object,and were divided into the control group(47 cases,receiving conventional drug therapy intervention) and the observation group(47 cases,receiving Xiyanping Injection on the basis of the control group) according to the difference in treatment methods.The clinical efficacy,levels of inflammatory factors(interleukin-6,C-reactive protein,procalcitonin) and clinical related symptoms were compared between the two groups.Results The total effective rate of treatment in the observation group was97.87%(46/47),which was higher than that of 85.11%(40/47) in the control group,and the difference was statistically significant(χ^(2)= 4.919,P=0.027).After treatment,the level of inflammatory factors,antipyretic time and the time of viral conversion decreased in both groups were all improved,and the observation group was better than the control group,and the differences were statistically significant(all P<0.05).The total incidence of adverse reactions in the observation groups were lower than those in the control group,and the difference were statistically significant(P<005).Conclusion The application of Xiyanping Injection in the treatment of pediatric rotavirus enteritis is beneficial to improve the clinical symptoms of children,reduce the level of inflammatory factors,so as to improve the therapeutic effect and promote the recovery of the disease.